In molecular biology, glycoside hydrolase family 88 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]
Glycoside hydrolase family 88 CAZY GH_88 includes enzymes with d-4,5 unsaturated β-glucuronyl hydrolase activity.[8][9]
^Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America. 92 (15): 7090–4. Bibcode:1995PNAS...92.7090H. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375.
^Davies G, Henrissat B (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–9. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
^Henrissat B, Bairoch A (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal. 316 (Pt 2): 695–6. doi:10.1042/bj3160695. PMC 1217404. PMID 8687420.
^"Home". CAZy.org. Retrieved 2018-03-06.
^Lombard V, Golaconda Ramulu H, Drula E, Coutinho PM, Henrissat B (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research. 42 (Database issue): D490–5. doi:10.1093/nar/gkt1178. PMC 3965031. PMID 24270786.
^"Glycoside Hydrolase Family 88". CAZypedia.org. Retrieved 2018-03-06.
^CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology. 28 (1): 3–8. doi:10.1093/glycob/cwx089. hdl:21.11116/0000-0003-B7EB-6. PMID 29040563.
^Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, et al. (1999). "Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases". Arch Biochem Biophys. 368 (2): 367–74. doi:10.1006/abbi.1999.1305. PMID 10441389.
^Ostrowski, Matthew P.; La Rosa, Sabina Leanti; Kunath, Benoit J.; Robertson, Andrew; Pereira, Gabriel; Hagen, Live H.; Varghese, Neha J.; Qiu, Ling; Yao, Tianming; Flint, Gabrielle; Li, James; McDonald, Sean P.; Buttner, Duna; Pudlo, Nicholas A.; Schnizlein, Matthew K.; Young, Vincent B.; Brumer, Harry; Schmidt, Thomas M.; Terrapon, Nicolas; Lombard, Vincent; Henrissat, Bernard; Hamaker, Bruce; Eloe-Fadrosh, Emiley A.; Tripathi, Ashootosh; Pope, Phillip B.; Martens, Eric C. (April 2022). "Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota". Nature Microbiology. 7 (4): 556–569. doi:10.1038/s41564-022-01093-0. hdl:11250/3003739. PMID 35365790. S2CID 247866305.
and 20 Related for: Glycoside hydrolase family 88 information
In molecular biology, glycosidehydrolasefamily88 is a family of glycosidehydrolases. Glycosidehydrolases EC 3.2.1. are a widespread group of enzymes...
K (July 2006). "A novel glycosidehydrolasefamily 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide...
by animals that forms part of the innate immune system. It is a glycosidehydrolase that catalyzes the following process: Hydrolysis of (1→4)-β-linkages...
bonds that immediately precede a (1,3) bond. Lichenases are from glycosidehydrolasefamily 16, and share a jellyroll structure. A deep surface cleft acts...
available in the PDB (see links in the infobox). A member of the glycosidehydrolasefamily, myrosinase possesses several similarities with the more ubiquitous...
occur naturally and are used for the fluorimetric determination of glycosidehydrolase enzymes. Isoprenylated derivatives are also widespread, such as marmin...
Dispersin B (also known as DspB or DispersinB) is a 40 kDa glycosidehydrolase produced by the periodontal pathogen, Aggregatibacter actinomycetemcomitans...
contains genes associated with breaking down polysaccharides, including glycosidehydrolases and starch binding proteins. These genes along with ECF-type sigma...
still be further converted into xanthophylls by using beta-hydrolase and epsilon-hydrolase, leading to a variety of xanthophylls. It is believed that...
another paracetamol metabolite 4-aminophenol by action of fatty acid amide hydrolase. AM404 is a weak agonist of cannabinoid receptors CB1 and CB2, an inhibitor...
perforatum, commonly known as St John's wort, is a flowering plant in the family Hypericaceae. It is a perennial plant that grows up to one meter tall, with...
variety of degradative enzymes, such as beta-glucosidase, protease, glycosidehydrolase, and chitinase. As a result, C. cellulans is capable of biodegrading...
Within Pteridophyta and Pinophyta, kaempferol has been found in diverse families. Kaempferol has also been identified in Dicotyledons and Monocotyledons...
elegans remain to be elucidated. Hexosaminidases (Hex) are important glycosidehydrolases for the generation of plant-specific paucimannosidic proteins across...
K, Roy Chowdhury A, Chatterjee R, Chakravortty D, 2022, GH18 familyglycosidehydrolase Chitinase A of Salmonella enhances virulence by facilitating invasion...