Glutamatergic means "related to glutamate". A glutamatergic agent (or drug) is a chemical that directly modulates the excitatory amino acid (glutamate/aspartate) system in the body or brain. Examples include excitatory amino acid receptor agonists, excitatory amino acid receptor antagonists, and excitatory amino acid reuptake inhibitors.
Glutamatergic means "related to glutamate". A glutamatergic agent (or drug) is a chemical that directly modulates the excitatory amino acid (glutamate/aspartate)...
The form of plasticity known as long-term potentiation takes place at glutamatergic synapses in the hippocampus, neocortex, and other parts of the brain...
in patients with ADHD." The etiology of autism may include excessive glutamatergic mechanisms. In small studies, memantine has been shown to significantly...
tolerated by children with autism spectrum disorder. A dysfunction of glutamatergic neurotransmission, manifested as neuronal excitotoxicity, is hypothesized...
reuptake inhibition, and antihyperalgesic activity through modulation of glutamatergic transmission. Nefopam is effective for prevention of shivering during...
models, tianeptine inhibits the pathological stress-induced changes in glutamatergic neurotransmission in the amygdala and hippocampus. It may also facilitate...
dopaminergic, noradrenergic, serotonergic, histaminergic, cholinergic, and glutamatergic brain nuclei. The ARAS is composed of several neural circuits connecting...
phenylketonuria. L-Phenylalanine also inhibits neurotransmitter release at glutamatergic synapses in hippocampus and cortex with IC50 of 980 μM, a brain concentration...
are at least partly mediated by blocking the NMDA receptors in the glutamatergic inputs to D1-type medium spiny neurons in the nucleus accumbens. PCP...
Therefore, glutamatergic and GABAergic inputs are not exclusively inhibitory nor exclusively excitatory. The VTA receives glutamatergic afferents from...
models the subset of pathologic mechanisms of schizophrenia linked to glutamatergic signaling. The hypothesis was initially based on a set of clinical,...
vertical cells and radial cells are primarily glutamatergic. The descriptors GABAergic and glutamatergic refer to the neurotransmitter (GABA and glutamate...
calretinin-expressing neurons. The dorsal striatum receives significant glutamatergic inputs from the cortex, as well as dopaminergic inputs from the substantia...
proteins. In the brain, zinc is stored in specific synaptic vesicles by glutamatergic neurons and can modulate neuronal excitability. It plays a key role...
brain, and regulates the activity of dopaminergic, serotonergic and glutamatergic systems. In the human gut, symbiotic bacteria convert dietary tryptophan...
the axon terminal of the presynaptic neuron, mainly at GABAergic and glutamatergic synapses. Neurotransmission is regulated by several different factors:...
to involve CB1 receptors as well as GABAergic and glutamatergic interactions. Cortical glutamatergic transmission may be modulated by endocannabinoids...
striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary...
exposure to psychostimulants increases glutamatergic [signaling] from the prefrontal cortex to the NAc. Glutamatergic signaling elevates Ca2+ levels in NAc...
neurotoxin which is structurally similar to phenylalanine, and is a glutamatergic agonist. Like the grapefruit, carambola is considered to be a potent...
memantine, it reduces excitotoxicity mediated by overactivation of the glutamatergic system by blocking NMDA receptor without sacrificing safety. Provisional...
initiation of locomotion. Neurons involved in each of these include glutamatergic, noradrenergic (NA), dopaminergic (DA), and serotonergic (5-HT) neurons...
in the presynaptic terminals of GABAergic (amygdala and cerebellum), glutamatergic (cortex, hippocampus and amygdala), dopaminergic, GABAergic interneurons...
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