Look up gene product or gene products in Wiktionary, the free dictionary.
A gene product is the biochemical material, either RNA or protein, resulting from expression of a gene. A measurement of the amount of gene product is sometimes used to infer how active a gene is. Abnormal amounts of gene product can be correlated with disease-causing alleles, such as the overactivity of oncogenes which can cause cancer.[1][2]
A gene is defined as "a hereditary unit of DNA that is required to produce a functional product".[3] Regulatory elements include:
Promoter region
TATA box
Polyadenylation sequences
Enhancers
These elements work in combination with the open reading frame to create a functional product. This product may be transcribed and be functional as RNA or is translated from mRNA to a protein to be functional in the cell.
^Fearon ER, Vogelstein B (June 1990). "A genetic model for colorectal tumorigenesis". Cell. 61 (5): 759–67. doi:10.1016/0092-8674(90)90186-I. PMID 2188735. S2CID 22975880.
^Croce CM (January 2008). "Oncogenes and cancer". The New England Journal of Medicine. 358 (5): 502–11. doi:10.1056/NEJMra072367. PMID 18234754.
^Nussbaum, Robert L.; McInnes, Roderick R.; Willard, Huntington (2016). Thompson & Thompson Genetics in Medicine (8 ed.). Philadelphia: Elsevier.
gene - surprisingly, there is no definition that is entirely satisfactory. A gene is a DNA sequence that codes for a diffusible product. This product...
Gene expression is the process by which information from a gene is used in the synthesis of a functional geneproduct that enables it to produce end products...
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and geneproduct attributes across all species. More specifically...
included so that the reporter and the geneproduct will only minimally interfere with one another. Reporter genes can also be expressed by induction during...
brought gene ontology, which in some ways is a next step of gene nomenclature, because it aims to unify the representation of gene and geneproduct attributes...
Gene dosage is the number of copies of a particular gene present in a genome. Gene dosage is related to the amount of geneproduct (proteins or functional...
A Tax GeneProduct (Tax) is a nuclear protein that has a molecular weight of about 37,000 to 40,000 daltons. Tax is produced by members of the retroviral...
adenosylcobalamin are commercially available as supplement pills. The MMACHC geneproduct catalyzes the decyanation of cyanocobalamin as well as the dealkylation...
increase or decrease the production of specific geneproducts (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for...
alleles observed result in little or no change in the function of the geneproduct it codes for. However, sometimes different alleles can result in different...
self-regulating mechanisms to create a time-dependent oscillation of geneproduct expression. Toggle-switch Gardner et al. used mutual repression between...
pleiotropic gene. Mutation in a pleiotropic gene may have an effect on several traits simultaneously, due to the gene coding for a product used by a myriad...
K, Guo N, et al. (January 2003). "PANTHER: a browsable database of geneproducts organized by biological function, using curated protein family and subfamily...
of change in sequences. Mutations in genes can have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely...
amount of geneproduct a cell is able to express, though a variety of controls have evolved which tightly regulate gene expression. Changes in gene dosage...
involves eight geneproducts (His1, 2, 3, 4, 5, 6, 7, and 8) and it occurs in ten steps. This is possible because a single geneproduct has the ability...
two-hit rule for tumor suppressors, such as certain mutations in the p53 geneproduct. p53 mutations can function as a dominant negative, meaning that a mutated...
little or no geneproduct (often a protein). Although the other, standard allele still produces the standard amount of product, the total product is insufficient...
feedback as well as repression through a repressor encoded by the gene argR. The geneproduct of argR, ArgR an aporepressor, and arginine as a corepressor...
this step, the Le geneproduct (FUT3) can add another fucose producing Le(b) antigen. Thus, individuals with the Le gene but no Se gene will have red blood...
A structural gene is a gene that codes for any RNA or protein product other than a regulatory factor (i.e. regulatory protein). A term derived from the...
BCAM-AKT2 is a fusion gene that is specific and unique to high-grade serous ovarian cancer. Oncogenic fusion genes may lead to a geneproduct with a new or different...
variant of a gene) caused by a genetic mutation. Such mutations can cause a complete lack of production of the associated geneproduct or a product that does...
mutated geneproduct adversely affects the non-mutated geneproduct within the same cell. X-linked dominant disorders are caused by mutations in genes on the...
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