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GFAP stain information


In histology, the GFAP stain is done to determine whether cells contain glial fibrillary acidic protein, a protein found in glial cells.

It is useful for determining whether a tumour is of glial origin.[1]

  1. ^ Reyaz N, Tayyab M, Khan SA, Siddique T (2005). "Correlation of glial fibrillary acidic protein (GFAP) with grading of the neuroglial tumours". Journal of the College of Physicians and Surgeons Pakistan. 15 (8): 472–5. PMID 16202357.

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GFAP stain

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In histology, the GFAP stain is done to determine whether cells contain glial fibrillary acidic protein, a protein found in glial cells. It is useful for...

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Glial fibrillary acidic protein

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Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. It is a type III intermediate filament (IF) protein that...

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Glial scar

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processes, and increase synthesis of glial fibrillary acidic protein (GFAP). GFAP is an important intermediate filament protein that allows the astrocytes...

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Pituicyte

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specific intermediate filaments made up of glial fibrillary acidic protein (GFAP). Pituicytes are similar to astrocytes, another type of glial cell. Their...

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Astrogliosis

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regeneration does not occur in areas with an increase in GFAP and vimentin. Paradoxically, an increase in GFAP production is also specific to the minimization...

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Subependymal giant cell astrocytoma

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Subependymal giant cell astrocytoma GFAP stained microscopic section of a subependymal giant cell astrocytoma Specialty Neuro-Oncology ...

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Astrocyte

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Dougherty PM, Kajander KC, Carlton SM (November 1991). "Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic...

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Glymphatic system

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Astrocytes stained for GFAP (green) and aquaporin-4 (purple)...

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Myofibroblast

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myofibroblasts (especially if they have a stellate form) may also be positive for GFAP. There are many possible ways of myofibroblast development: Partial smooth...

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Immunostaining

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antibody-based staining methods. Immunohistochemistry or IHC staining of tissue sections (or immunocytochemistry, which is the staining of cells), is perhaps...

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Pilocytic astrocytoma

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the tumor is seen to be composed of bipolar cells with long "hair-like" GFAP-positive processes, giving the designation "pilocytic" (that is, made up...

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Cirrhosis

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epidermal growth factor and tumor growth factor-beta receptor signaling through GFAP-ACTA2 protein interaction in liver fibrosis". Pakistan Journal of Medical...

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Glia

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Glial cells in a rat brain stained with an antibody against GFAP...

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Keratin 8

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Cytokeratin 8 staining in the human breast cancer cell line MCF-7...

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Calyx of Held

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astrocytic cell from rat brain grown in tissue culture and stained with antibodies to GFAP (red) and vimentin (green). Both proteins are present in large...

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Choroid plexus papilloma

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papilloma patients may test positive for glial fibrillary acidic protein (GFAP). Studies have found that fourth ventricle cancers express more S100 than...

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Acral myxoinflammatory fibroblastic sarcoma

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not express CD45, CD15, CD30, HMB-45, MLANA (also termed Melan-A), desmin, GFAP, or S100 proteins. Earlier studies had reported that these cells express...

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Proteinopathy

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PMID 10712425. Quinlan RA, Brenner M, Goldman JE, Messing A (June 2007). "GFAP and its role in Alexander disease". Experimental Cell Research. 313 (10):...

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Adult neurogenesis

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which can be used as antigens in an immunoassay. For example, NeuN/Fox3 and GFAP are antigens commonly used to detect neurons, glia, and ependymal cells....

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Radial glial cell

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and, in some instances, including humans, glial fibrillary acidic protein (GFAP). After this transition, radial glia retain many of the original characteristics...

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Angiocentric glioma

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fibrillary acidic protein (GFAP) and epithelial membrane antigen (EMA). Clinicians also observe a specific dot-like pattern from the stained EMA photomicrograph...

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Subgranular zone

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astrocytic in their morphology, their expression of glial markers such as GFAP, and their function in regulating the NSC microenvironment. However, unlike...

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Neuronal lineage marker

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different structures. The most important neural markers used nowadays are the GFAP, Nestin, NeuroD antibodies and others. For the past years there are still...

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Neurofilament light polypeptide

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divided into 5 major classes, the Class I and II keratins, Class III vimentin, GFAP, desmin and the others, the Class IV neurofilaments and the Class V nuclear...

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P19 cell

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astroglial cells can be detected using glial fibrillary acidic protein (GFAP), which is a specific marker of glial cells. Other than into neurons and...

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Tau protein

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Neurons were grown in tissue culture and stained with antibody to MAP2 protein in green and MAP tau in red using the immunofluorescence technique. MAP2...

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Gemistocyte

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cytoplasmic filaments. The cytoplasm of gemistocytes stains positive for glial fibrillary acidic protein, GFAP. While the intermediate filaments in gemistocytes...

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Folliculostellate cell

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cell markers, including GFAP (glial fibrillary acidic protein), cytokeratin, vimentin and fibronectin. S-100 protein and GFAP expression seem to be strongest...

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