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Fracture of biological materials information


Fracture of biological materials may occur in biological tissues making up the musculoskeletal system, commonly called orthopedic tissues: bone, cartilage, ligaments, and tendons. Bone and cartilage, as load-bearing biological materials, are of interest to both a medical and academic setting for their propensity to fracture. For example, a large health concern is in preventing bone fractures in an aging population, especially since fracture risk increases ten fold with aging.[1] Cartilage damage and fracture can contribute to osteoarthritis, a joint disease that results in joint stiffness and reduced range of motion.

Biological materials, especially orthopedic materials, have specific material properties which allow them to resist damage and fracture for a prolonged period of time. Nevertheless, acute damage or continual wear through a lifetime of use can contribute to breakdown of biological materials. Studying bone and cartilage can motivate the design of resilient synthetic materials that could aid in joint replacements. Similarly, studying polymer fracture and soft material fracture could aid in understanding biological material fracture.

The analysis of fracture in biological materials is complicated by multiple factors such as anisotropy, complex loading conditions, and the biological remodeling response and inflammatory response.

  1. ^ Hui, S L; Slemenda, C W; Johnston, C C (1988-06-01). "Age and bone mass as predictors of fracture in a prospective study". Journal of Clinical Investigation. 81 (6): 1804–1809. doi:10.1172/jci113523. ISSN 0021-9738. PMC 442628. PMID 3384952.

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