Fatty acid amides (FAAs) are amides formed from a fatty acid and an amine. In nature, many FAAs have ethanolamine as the amine component. Also known as N-acylethanolamines, they contain the functionality RC(O)N(H)CH2CH2OH. A well known example is anandamide. Other fatty acid amides are fatty acid primary amides (FAPAs). They contain the functionality RC(O)NH2). Oleamide is an example of this class of FAPAs.[1]
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butanol and isopropanol. Fattyacid ethyl esters are biomarkers for the consumption of ethanol (alcoholic beverages). Fattyacidamide Pragst, F; Yegles, M...
the amide derived from the fattyacid oleic acid. It is a colorless waxy solid and occurs in nature. Sometimes labeled as a fattyacid primary amide (FAPA)...
on the glial cell and degraded by fattyacidamide hydrolase (FAAH), which cleaves anandamide into arachidonic acid and ethanolamine or monoacylglycerol...
brain from another paracetamol metabolite 4-aminophenol by action of fattyacidamide hydrolase. AM404 is a weak agonist of cannabinoid receptors CB1 and...
Linoleic acid (LA) is an organic compound with the formula HOOC(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups (−CH=CH−) are cis. It is a fattyacid sometimes...
deaminase (ambiguous), fatty acylamidase, N-acetylaminohydrolase (ambiguous)) is an enzyme that catalyzes the hydrolysis of an amide. In this way, the two...
citation needed] It has also been found to be a weak inhibitor of fattyacidamide hydrolase in vitro. The enzyme biochanin-A reductase uses dihydrobiochanin...
Palmitoylethanolamide (PEA) is an endogenous fattyacidamide, and lipid modulator PEA has been studied in in vitro and in vivo systems using exogenously...
delight", plus amide. Anandamide is derived from the non-oxidative metabolism of arachidonic acid, an essential omega-6 fattyacid. It is synthesized...
Earlier work on the mechanism of AM404 suggested that the inhibition of fattyacidamide hydrolase (FAAH) by AM404 was responsible for all of its attributed...
Behenic acid (also docosanoic acid) is a carboxylic acid, the saturated fattyacid with formula C21H43COOH. In appearance, it consists of white solid although...
is a relatively selective and irreversible inhibitor of the enzyme fattyacidamide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid...
acid, and the 15-lipoxygenase-derived products of the N-acetylated fattyacidamide of the DHA metabolite, docosahexaenoyl ethanolamide. MaR1 was first...
Oleic acid is a fattyacid that occurs naturally in various animal and vegetable fats and oils. It is an odorless, colorless oil, although commercial samples...
a major subclass of sphingoid base derivatives with an amide-linked fattyacid. The fattyacids are typically saturated or mono-unsaturated with chain...
acetaminophen to the bioactive N-acylphenolamine AM404 via fattyacidamide hydrolase-dependent arachidonic acid conjugation in the nervous system". The Journal...
information integration capacity. Propofol is an inhibitor of the enzyme fattyacidamide hydrolase, which metabolizes the endocannabinoid anandamide (AEA)....
monotopic domains of transmembrane proteins: monoamine oxidases A and B fattyacidamide hydrolase mammalian cytochrome P450 oxidases corticosteroid 11-beta-dehydrogenases...
In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R″, where R, R', and...