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Factor D information


complement factor D (adipsin)
Factor D in Homo sapiens[1][2]
Identifiers
SymbolCFD
Alt. symbolsDF, PFD
NCBI gene1675
HGNC2771
OMIM134350
RefSeqNM_001928
UniProtP00746
Other data
LocusChr. 19 p13.3
Search for
StructuresSwiss-model
DomainsInterPro

Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) is a protein which in humans is encoded by the CFD gene.[3] Factor D is involved in the alternative complement pathway of the complement system where it cleaves factor B.

  1. ^ PDB: 1HFD
  2. ^ Narayana SV, Carson M, el-Kabbani O, Kilpatrick JM, Moore D, Chen X, Bugg CE, Volanakis JE, DeLucas LJ (1994). "Structure of human factor D. A complement system protein at 2.0 A resolution". Journal of Molecular Biology. 235 (2): 695–708. doi:10.1006/jmbi.1994.1021. PMID 8289289.
  3. ^ EntrezGene 1675

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