FOXH1 information

FOXH1
Identifiers
Aliases	FOXH1, FAST-1, FAST1, forkhead box H1
External IDs	OMIM: 603621; MGI: 1347465; HomoloGene: 2914; GeneCards: FOXH1; OMA:FOXH1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	144,475,849 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	76,554,148 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; mucosa of transverse colon; ; islet of Langerhans; ; middle temporal gyrus; ; rectum; ; mucosa of nose; ; duodenum; ; nucleus accumbens; ; occipital lobe;
	Top expressed in
	epiblast; ; embryo; ; lumbar spinal ganglion; ; embryo; ; blastocyst; ; primitive endoderm; ; primitive streak; ; spermatid; ; morula; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	co-SMAD binding; transcription coregulator activity; protein domain specific binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; androgen receptor binding; DNA-binding transcription factor activity; bHLH transcription factor binding; DNA binding; protein binding; R-SMAD binding; SMAD binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; activin responsive factor complex; transcription regulator complex; nucleus;
Biological process	ventricular trabecula myocardium morphogenesis; anterior/posterior pattern specification; negative regulation of androgen receptor signaling pathway; embryonic heart tube anterior/posterior pattern specification; transcription, DNA-templated; outflow tract morphogenesis; nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; regulation of transcription by RNA polymerase II; heart looping; axial mesoderm development; cardiac right ventricle morphogenesis; negative regulation of transcription by RNA polymerase II; determination of left/right symmetry; secondary heart field specification; positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; aorta morphogenesis; transcription by RNA polymerase II; negative regulation of intracellular estrogen receptor signaling pathway; transforming growth factor beta receptor signaling pathway; positive regulation of transcription by RNA polymerase II; cellular response to cytokine stimulus; anatomical structure morphogenesis; cell differentiation; negative regulation of DNA-binding transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	8928
	14106
	ENSG00000160973
	ENSMUSG00000033837
	O75593
	O88621
	NM_003923
	NM_007989
	NP_003914
	NP_032015
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein H1 is a protein that in humans is encoded by the FOXH1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000160973 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033837 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B (July 1998). "Characterization of human FAST-1, a TGF beta and activin signal transducer". Molecular Cell. 2 (1): 121–127. doi:10.1016/S1097-2765(00)80120-3. PMID 9702198.
^ "Entrez Gene: FOXH1 forkhead box H1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000160973 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033837 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9702198-5] Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B (July 1998). "Characterization of human FAST-1, a TGF beta and activin signal transducer". Molecular Cell. 2 (1): 121–127. doi:10.1016/S1097-2765(00)80120-3. PMID 9702198.

[entrez-6] "Entrez Gene: FOXH1 forkhead box H1".

FOXH1 information

and 10 Related for: FOXH1 information

FOXH1

Oocyte

List of human transcription factors

Nodal signaling pathway

FOX proteins

SNIP1

Mothers against decapentaplegic homolog 2

Nodal homolog

CCDC94

DRAP1