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Excitatory amino acid receptor antagonist information


An excitatory amino acid receptor antagonist, or glutamate receptor antagonist, is a chemical substance which antagonizes one or more of the glutamate receptors.[1]

Examples include:

  • AP5
  • Barbiturates
  • Dextromethorphan
  • Dextrorphan
  • Dizocilpine
  • Ethanol
  • Ibogaine
  • Ifenprodil
  • Ketamine
  • Kynurenic acid
  • Memantine
  • Nitrous oxide
  • Perampanel
  • Phencyclidine
  1. ^ Excitatory+amino+acid+antagonists at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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Excitatory amino acid receptor antagonist

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An excitatory amino acid receptor antagonist, or glutamate receptor antagonist, is a chemical substance which antagonizes one or more of the glutamate...

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Excitatory amino acid receptor agonist

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Glutamic acid Ibotenic acid Kainic acid N-Methyl-D-aspartic acid Quisqualic acid Excitatory amino acid receptor antagonist Excitatory amino acid reuptake...

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Excitatory amino acid receptor ligand

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glutamate receptors. They include excitatory amino acid receptor agonists and excitatory amino acid receptor antagonists. Christensen, Inge T.; Ebert, Bjarke;...

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Excitatory amino acid reuptake inhibitor

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inhibitor Glycine reuptake inhibitor Excitatory amino acid receptor agonist Excitatory amino acid receptor antagonist J. Storm-Mathisen; O.P. Ottersen (3...

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Kynurenic acid

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and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important...

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NMDA receptor antagonist

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Muir KW, Lees KR (March 1995). "Clinical experience with excitatory amino acid antagonist drugs". Stroke. 26 (3): 503–13. doi:10.1161/01.STR.26.3.503...

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Glutamate receptor

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strength. 2. AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors: These receptors mediate the majority of fast excitatory synaptic transmission...

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NMDA receptor

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moderate affinity uncompetitive NMDA receptor antagonist: preclinical summary and clinical experience". Amino Acids. 19 (1): 177–179. doi:10.1007/s007260070047...

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AMPA receptor

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The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane...

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Kainic acid

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Kainic acid, or kainate, is an acid that naturally occurs in some seaweed. Kainic acid is a potent neuroexcitatory amino acid agonist that acts by activating...

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Glutamic acid

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Glutamic acid (symbol Glu or E; the anionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis...

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Neurotransmitter

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neurotransmitters include amino acids, monoamines, and peptides. Monoamines are synthesized by altering a single amino acid. For example, the precursor...

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Glycine receptor

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The glycine receptor (abbreviated as GlyR or GLR) is the receptor of the amino acid neurotransmitter glycine. GlyR is an ionotropic receptor that produces...

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Glutamatergic

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excitatory amino acid receptor agonists, excitatory amino acid receptor antagonists, and excitatory amino acid reuptake inhibitors. Adenosinergic Adrenergic Cannabinoidergic...

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AMPA

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α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, better known as AMPA, is a compound that is a specific agonist for the AMPA receptor, where it mimics...

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Quisqualic acid

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identified as the quisqualate receptor. Instead, it demonstrates high affinity for other types of excitatory amino acid receptors, including kainate, AMPA...

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Glycine

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/ˈɡlaɪsiːn/ ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid (carbamic acid is unstable). In the...

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Phenylalanine

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Phenylalanine (symbol Phe or F) is an essential α-amino acid with the formula C 9H 11NO 2. It can be viewed as a benzyl group substituted for the methyl...

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Domoic acid

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Domoic acid is an excitatory amino acid analogue of glutamate; a neurotransmitter in the brain that activates glutamate receptors. Domoic acid has a very strong...

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Quinolinic acid

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Quinolinic acid is a downstream product of the kynurenine pathway, which metabolizes the amino acid tryptophan. It acts as an NMDA receptor agonist. Quinolinic...

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Theanine

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L-gamma-glutamylethylamide or N5-ethyl-L-glutamine, is an amino acid analogue of the proteinogenic amino acids L-glutamate and L-glutamine and is found primarily...

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GHB receptor

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The γ-hydroxybutyrate (GHB) receptor (GHBR), originally identified as GPR172A, is an excitatory G protein-coupled receptor (GPCR) that binds the neurotransmitter...

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Metabotropic glutamate receptor

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G-protein-coupled receptors, or GPCRs. Like all glutamate receptors, mGluRs bind with glutamate, an amino acid that functions as an excitatory neurotransmitter...

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Homocysteic acid

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acid is the organosulfur compound with the formula HO3SCH2CH2CH(NH2)CO2H. A white solid, it is sulfonic acid-containing non-proteinogenic amino acid....

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Aspartic acid

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Aspartic acid (symbol Asp or D; the ionic form is known as aspartate), is an α-amino acid that is used in the biosynthesis of proteins. The L-isomer of...

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