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Eukaryotic translation termination factor 1 information


ETF1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesETF1, D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1, eukaryotic translation termination factor 1
External IDsOMIM: 600285; MGI: 2385071; HomoloGene: 3475; GeneCards: ETF1; OMA:ETF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_144866

RefSeq (protein)

NP_659115

Location (UCSC)Chr 5: 138.51 – 138.54 MbChr 18: 35.04 – 35.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation termination factor 1 (eRF1), also referred to as TB3-1 or SUP45L1, is a protein that is encoded by the ERF1 gene. In Eukaryotes, eRF1 is an essential protein involved in stop codon recognition in translation, termination of translation, and nonsense mediated mRNA decay via the SURF complex.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120705 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024360 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "ETF1 eukaryotic translation termination factor 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2024-03-30.

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Eukaryotic translation termination factor 1

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Eukaryotic translation termination factor 1 (eRF1), also referred to as TB3-1 or SUP45L1, is a protein that is encoded by the ERF1 gene. In Eukaryotes...

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Eukaryotic translation

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Eukaryotic translation is the biological process by which messenger RNA is translated into proteins in eukaryotes. It consists of four phases: initiation...

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Eukaryotic transcription

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each translating a different type of gene. A eukaryotic cell has a nucleus that separates the processes of transcription and translation. Eukaryotic transcription...

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Elongation factor

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machinery, eukaryotic mitochondria and plastids have their own translation machinery, each with their own set of bacterial-type elongation factors. In humans...

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Eukaryotic initiation factor

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Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. These proteins help...

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Release factor

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A release factor is a protein that allows for the termination of translation by recognizing the termination codon or stop codon in an mRNA sequence. They...

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RNA polymerase

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transcription and translation?". Retrieved 26 March 2019. Richardson JP (September 2002). "Rho-dependent termination and ATPases in transcript termination". Biochimica...

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Bacterial translation

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Bacterial translation is the process by which messenger RNA is translated into proteins in bacteria. Initiation of translation in bacteria involves the...

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Open reading frame

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before the stop codon, an incomplete protein would be made during translation. In eukaryotic genes with multiple exons, introns are removed and exons are then...

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Start codon

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are functional as translation start sites in mammalian cells. Bacteria do not generally have the wide range of translation factors monitoring start codon...

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Archaeal translation

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protein level it seems to resemble eukaryotic translation. Most of the initiation, elongation, and termination factors in archaea have homologs in eukaryotes...

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Translational regulation

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interaction. Mechanistically, eukaryotic translation termination matches its prokaryotic counterpart. In this case, termination of the polypeptide chain is...

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Ribosome recycling factor

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Ribosome recycling factor or ribosome release factor (RRF) is a protein found in bacterial cells as well as eukaryotic organelles, specifically mitochondria...

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Messenger RNA

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"Circularization of mRNA by eukaryotic translation initiation factors". Molecular Cell. 2 (1): 135–140. CiteSeerX 10.1.1.320.5704. doi:10.1016/S1097-2765(00)80122-7...

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Split gene theory

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theory is a theory of the origin of introns, long non-coding sequences in eukaryotic genes between the exons. The theory holds that the randomness of primordial...

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DNA replication

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"The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases". Cell Research. 18 (1): 148–161. doi:10.1038/cr.2008.4...

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Five prime untranslated region

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complexity of the eukaryotic regulation which the 5′ UTR holds as well as the larger pre-initiation complex that must form to begin translation. The 5′ UTR...

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EIF4A

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The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the...

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Bacterial transcription

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Bacterial transcription differs from eukaryotic transcription in several ways. In bacteria, transcription and translation can occur simultaneously in the cytoplasm...

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Sup35p

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eukaryotic translation release factor. More specifically, it is the yeast eukaryotic release factor 3 (eRF3), which forms the translation termination...

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PABPC1

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Katada T (June 1999). "The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail...

Word Count : 1663

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