Eribulin, sold under the brand name Halaven among others, is an anti-cancer medication used to treat breast cancer and liposarcoma.[4][5]
The most common side effects include fatigue, nausea, hair loss (alopecia), constipation, certain nerve damage causing weakness or numbness in the hands and feet (peripheral neuropathy), abdominal pain and fever (pyrexia).[10] Eribulin may also cause low levels of infection-fighting white blood cells (neutropenia) or decreased levels of potassium or calcium.[10]
Eribulin was approved for medical use in the United States in November 2010,[11] the European Union in March 2011,[5] and Canada in December 2011.[2][12][13] It is available as a generic medication.[6]
^"Eribulin (Halaven) Use During Pregnancy". Drugs.com. 22 October 2019. Retrieved 9 July 2020.
^ ab"Halaven Product information". Health Canada. 22 October 2009. Retrieved 16 December 2023.
^"Halaven 0.44 mg/ml solution for injection". (emc). 16 January 2023. Retrieved 16 December 2023.
^ ab"Halaven- eribulin mesylate injection". DailyMed. 22 December 2017. Retrieved 9 July 2020.
^ abc"Halaven EPAR". European Medicines Agency (EMA). 17 March 2011. Retrieved 16 December 2023.
^ ab"Mevlyq EPAR". European Medicines Agency (EMA). 9 February 2024. Retrieved 19 February 2024.
^"Mevlyq product information". Union Register of medicinal products. 13 February 2024. Retrieved 19 February 2024.
^"Eisai Announces Japan Launch Of Anticancer Agent Halaven" (Press release). Eisai Co., Ltd. 19 July 2011. Retrieved 15 February 2021.
^"Anticancer Agent Halaven Approved For Treatment Of Locally Advanced Or Metastatic Breast Cancer In China" (Press release). Eisai Co., Ltd. 17 July 2019. Retrieved 15 February 2021.
^ abCite error: The named reference FDA-lipo2016 was invoked but never defined (see the help page).
^"Drug Approval Package: Halaven (erbulin mesylate) NDA 201532". U.S. Food and Drug Administration (FDA). Retrieved 9 July 2020.
^"Halaven for Metastatic Breast Cancer". Canadian Agency for Drugs and Technologies in Health. 9 March 2015. Retrieved 9 July 2020.
^"Eisai Announces Canadian Approval of its Anticancer Agent Halaven". Eisai Co., Ltd. (Press release). Retrieved 9 July 2020.
Eribulin, sold under the brand name Halaven among others, is an anti-cancer medication used to treat breast cancer and liposarcoma. The most common side...
simplified and pharmaceutically optimized analog eribulin (E7389, ER-086526, NSC-707389). Eribulin was approved by the U.S. Food and Drug Administration...
Phase 1b/2 Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects...
three weeks and 184 randomly received physician's choice of chemotherapy (eribulin, capecitabine, gemcitabine, nab paclitaxel, or paclitaxel). The results...
necessary with the natural product halichondrin B, its simplified analogue eribulin now approved and marketed as an anticancer drug. Errors and oversights...
polymerization of tubulin into microtubules. Eribulin binds to the (+) growing end of the microtubules. Eribulin exerts its anticancer effects by triggering...
anthracycline-based chemotherapy regimen or, in tumor-resistant or relapsed cases, eribulin chemotherapy. A review conducted in 2020 reported median survival times...