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Epigenetics of chronic pain is the study of how epigenetic modifications of genes affect the development and maintenance of chronic pain. Chromatin modifications have been found to affect neural function, such as synaptic plasticity and memory formation, which are important mechanisms of chronic pain. In 2019, 20% of adults dealt with chronic pain.[1] Epigenetics can provide a new perspective on the biological mechanisms and potential treatments of chronic pain.
^Descalzi G, Ikegami D, Ushijima T, Nestler EJ, Zachariou V, Narita M (April 2015). "Epigenetic mechanisms of chronic pain". Trends in Neurosciences. 38 (4): 237–246. doi:10.1016/j.tins.2015.02.001. PMC 4459752. PMID 25765319.
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