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Epigenetic effects of smoking information


Epigenetic effects of smoking concerns how epigenetics (hertiable characteristics that do not involve changes in DNA sequence) contributes to the deleterious effects of smoking. Cigarette smoking has been found to affect global epigenetic regulation of transcription across tissue types. Studies have shown differences in epigenetic markers like DNA methylation, histone modifications and miRNA expression between smokers and non-smokers. Similar differences exist in children whose mothers smoked during pregnancy. These epigenetic effects are thought to be linked to many of negative health effects associated with smoking.

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Epigenetic effects of smoking

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Epigenetic effects of smoking concerns how epigenetics (hertiable characteristics that do not involve changes in DNA sequence) contributes to the deleterious...

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Epigenetics

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inheritance. Epigenetics usually involves a change that is not erased by cell division, and affects the regulation of gene expression. Such effects on cellular...

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Smoking and pregnancy

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Tobacco smoking during pregnancy causes many detrimental effects on health and reproduction, in addition to the general health effects of tobacco. A number...

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Epigenetic clock

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An epigenetic clock is a biochemical test that can be used to measure age. The test is based on DNA methylation levels, measuring the accumulation of methyl...

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Smoking

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and rolling paper. Other smoking implements include pipes, cigars, bidis, hookahs, and bongs. Smoking has negative health effects, because smoke inhalation...

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Cigarette

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smaller size, use of processed leaf, and paper wrapping, which is typically white. There are significant negative health effects from smoking cigarettes such...

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Tobacco smoking

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Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or simply released...

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Behavioral epigenetics

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Behavioral epigenetics is the field of study examining the role of epigenetics in shaping animal and human behavior. It seeks to explain how nurture shapes...

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Epigenetics of autoimmune disorders

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autoimmune condition. Smoking, stress, and diet can produce epigenetic modifications to the genome that alter the regulation of immune system-specific...

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Epigenetic therapy

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Epigenetic therapy refers to the use of drugs or other interventions to modify gene expression patterns, potentially treating diseases by targeting epigenetic...

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Nicotine

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placebo-controlled studies concluded that nicotine or smoking had significant positive effects on aspects of fine motor abilities, alerting and orienting attention...

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Epigenetic priming

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Epigenetic priming (also known as gene priming) is the modification to a cell's epigenome whereby specific chromatin domains within a cell are converted...

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Epigenetics of schizophrenia

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The epigenetics of schizophrenia is the study of how inherited epigenetic changes are regulated and modified by the environment and external factors and...

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Brain health and pollution

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high blood pressure and smoking are known to increase the risk of developing dementia. The Committee on the Medical Effects of Air Pollutants (COMEAP)...

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Addiction

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addiction to cocaine. As of 2018,[update] neither the heritability of these epigenetic marks in humans nor the behavioral effects of the marks within human...

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Methamphetamine

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shorter psychodynamic effects. The bioavailability of methamphetamine is 67% orally, 79% intranasally, 67 to 90% via inhalation (smoking), and 100% intravenously...

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Aneuploidy

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involved in aneuploidy formation, specifically on the epigenetic origin of aneuploid cells. Epigenetic inheritance is defined as cellular information other...

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Regulation of gene expression

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LC, Reynolds LM, Mandaviya PR, et al. (October 2016). "Epigenetic Signatures of Cigarette Smoking". Circulation: Cardiovascular Genetics. 9 (5): 436–447...

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Inflammation

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epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues". Proceedings of the National Academy of Sciences of the...

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Epiphenotyping

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background of epiphenotyping, an overview of a general methodology, its applications, advantages, and limitations are covered. Epigenetics refers to heritable...

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Transgenerational trauma

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increased smoking/alcohol use), or perhaps through stress-induced epigenetic modifications in utero and early life. Historical trauma, a sub-type of transgenerational...

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Epigenetics of neurodegenerative diseases

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thought to have an epigenetic cause. Some factors that may increase the incidence of MS are smoking, vitamin deficiency, and a history of some viral infections—which...

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Cocaine

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to cocaine may lead to the breakdown of the blood–brain barrier. Physical side effects from chronic smoking of cocaine include coughing up blood, bronchospasm...

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Colorectal cancer

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programmed cell death, antiproliferative effects, and epigenetic modification of cancer cells. Mouse models of colorectal and intestinal cancer have been...

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Air pollution

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neurodevelopmental disorders in children is thought to be related to epigenetic dysregulation of the primordial germ cells, embryo, and fetus during a critical...

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Pharmacoepigenetics

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Pharmacoepigenetics is an emerging field that studies the underlying epigenetic marking patterns that lead to variation in an individual's response to...

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