H&E Stain: Dense Eosinophilic infiltration of gastro-duodenal wall
Specialty
Immunology, Gastroenterology
Eosinophilic gastroenteritis (EG or EGE), also known as eosinophilic enteritis,[1] is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.[2][3] Presentation may vary depending on location as well as depth and extent of bowel wall involvement and usually runs a chronic relapsing course. It can be classified into mucosal, muscular and serosal types based on the depth of involvement.[4][5] Any part of the GI tract can be affected, and isolated biliary tract involvement has also been reported.[6][7]
The stomach is the organ most commonly affected, followed by the small intestine and the colon.[8][9]
^Pineton de Chambrun, Guillaume; Dufour, Gaspard; Tassy, Barbara; Rivière, Benjamin; Bouta, Najima; Bismuth, Michael; Panaro, Fabrizio; Funakoshi, Natalie; Ramos, Jeanne; Valats, Jean-Christophe; Blanc, Pierre (2018-07-02). "Diagnosis, Natural History and Treatment of Eosinophilic Enteritis: a Review". Current Gastroenterology Reports. 20 (8): 37. doi:10.1007/s11894-018-0645-6. ISSN 1534-312X.
^Kaijser R. Zur Kenntnis der allergischen Affektionen des Verdauugskanals vom Standpunkt des Chirurgen aus. Arch Klin Chir 1937; 188:36–64.
^Whitaker I, Gulati A, McDaid J, Bugajska-Carr U, Arends M (2004). "Eosinophilic gastroenteritis presenting as obstructive jaundice". European Journal of Gastroenterology & Hepatology. 16 (4): 407–9. doi:10.1097/00042737-200404000-00007. PMID 15028974.
^Klein N, Hargrove R, Sleisenger M, Jeffries G (1970). "Eosinophilic gastroenteritis". Medicine (Baltimore). 49 (4): 299–319. doi:10.1097/00005792-197007000-00003. PMID 5426746. S2CID 45969740.
^Treiber, Treiber; Weidner, S (2007). "Eosinophilic Gastroenteritis". Clinical Gastroenterology and Hepatology. 5 (5): e16. doi:10.1016/j.cgh.2007.01.011. PMID 17428742.
^Polyak S, Smith T, Mertz H (2002). "Eosinophilic gastroenteritis causing pancreatitis and pancreaticobiliary ductal dilation". Dig. Dis. Sci. 47 (5): 1091–5. doi:10.1023/A:1015046309132. PMID 12018905. S2CID 24453648.
^Christopher V, Thompson M, Hughes S (2002). "Eosinophilic gastroenteritis mimicking pancreatic cancer". Postgraduate Medical Journal. 78 (922): 498–9. doi:10.1136/pmj.78.922.498. PMC 1742453. PMID 12185230.
^Naylor A (1990). "Eosinophilic gastroenteritis". Scottish Medical Journal. 35 (6): 163–5. doi:10.1177/003693309003500601. PMID 2077646. S2CID 43539786.
^Jimenez-Saenz M, Villar-Rodriguez J, Torres Y, Carmona I, Salas-Herrero E, Gonzalez-Vilches J, Herrerias-Gutierrez J (2003). "Biliary tract disease: a rare manifestation of eosinophilic gastroenteritis". Dig. Dis. Sci. 48 (3): 624–7. doi:10.1023/A:1022521707420. PMID 12757181. S2CID 23627059.
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