Eosinophilic fasciitis (/ˌiːəˌsɪnəˈfɪlɪkˌfæʃiˈaɪtɪs,ˌiːoʊ-,-ˌfæsi-/[2][3]), also known as Shulman's syndrome,[4] is an inflammatory disease that affects the fascia, other connective tissues, surrounding muscles, blood vessels and nerves. Unlike other forms of fasciitis, eosinophilic fasciitis is typically self-limited and confined to the arms and legs, although it can require treatment with corticosteroids, and some cases are associated with aplastic anemia.[5]
The condition was first characterized in 1974,[6] but it is not yet known whether it is actually a distinct condition or merely a variant presentation of another syndrome. The presentation is similar to that of scleroderma or systemic sclerosis. However, unlike scleroderma, eosinophilic fasciitis affects the deeper fascial layers, rather than the dermis; the characteristic and severe effects of scleroderma and systemic sclerosis, such as Raynaud's syndrome, involvement of the extremities, prominent small blood vessels (telangiectasias), and visceral changes such as swallowing problems, are absent. Nevertheless, the term remains used for diagnostic purposes.[citation needed]
^"Eosinophilic fasciitis: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 29 October 2019.
^"Eosinophilic". Lexico UK English Dictionary. Oxford University Press. Archived from the original on 2020-03-22. "fasciitis". Oxford Dictionaries UK English Dictionary. Oxford University Press.[dead link]
Eosinophilicfasciitis (/ˌiːəˌsɪnəˈfɪlɪk ˌfæʃiˈaɪtɪs, ˌiːoʊ-, -ˌfæsi-/), also known as Shulman's syndrome, is an inflammatory disease that affects the...
category of fibroblastic and myofibroblastic tumors. Eosinophilicfasciitis Paraneoplastic fasciitis "fasciitis". TheFreeDictionary. Retrieved 20 January 2014...
a more serious disease such as the hypereosinophilic syndrome, eosinophilicfasciitis, or the Churg-Strauss syndrome. Several case reports have found...
syndrome is a form of eosinophilia caused by L-tryptophan supplements. Eosinophilicfasciitis affects the connective tissue surrounding skeletal muscles, bones...
features which overlap other types of fasciitis disorders such as proliferative fasciitis and nodular fasciitis. However, the age, history of debilitation...
tissue, including fascia, and there is a clinical overlap with eosinophilicfasciitis, eosinophilia-myalgia syndrome, and the Spanish toxic oil syndrome...
spreading to the surrounding neck muscles and causing cervical necrotizing fasciitis which is a surgical emergency. The differential diagnosis includes other...
grouped into nests, sheets, cords, and/or single files embedded in an eosinophilic (i.e. more blue or purple compared to normal connective tissue because...
classic PTC (b). In the tall cell variant of PTC, the cytoplasm is deeply eosinophilic, and nuclear features of PTC are very prominent with irregular contours...
infarcted patches of myocytes. Necrotic muscle fibers are swollen and eosinophilic and lack striations and nuclei. Small-vessel walls are thickened and...
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