Micrograph showing the yolk sac component of a mixed germ cell tumour. H&E stain.
Specialty
Oncology
Endodermal sinus tumor (EST) is a member of the germ cell tumor group of cancers.[1] It is the most common testicular tumor in children under three,[2] and is also known as infantile embryonal carcinoma. This age group has a very good prognosis. In contrast to the pure form typical of infants, adult endodermal sinus tumors are often found in combination with other kinds of germ cell tumor, particularly teratoma and embryonal carcinoma. While pure teratoma is usually benign, endodermal sinus tumor is malignant.
^"Endodermal Sinus Tumor". Retrieved 2018-10-10.
^Hari, Anil; Grossfeld, Gary; Hricak, Hedvig (2002-01-01), Bragg, David G.; Rubin, Philip; Hricak, Hedvig (eds.), "Chapter 29 - Tumors of the Scrotum", Oncologic Imaging, Oxford: Elsevier, pp. 603–628, doi:10.1016/b0-72-167494-1/50032-3, ISBN 978-0-7216-7494-0, retrieved 2020-10-21
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