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Endocrine therapy resistance in breast cancer information


Endocrine therapy is a common treatment for estrogen receptor positive breast cancer. However, resistance to this therapy can develop, leading to relapse and progression of disease. This highlights the need for new strategies to combat this resistance.

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Endocrine therapy resistance in breast cancer

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Endocrine therapy is a common treatment for estrogen receptor positive breast cancer. However, resistance to this therapy can develop, leading to relapse...

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Breast cancer

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Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling...

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Feminizing hormone therapy

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disease, especially in older and obese people. Studies are mixed on whether the risk of breast cancer is increased with hormone therapy in transgender women...

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Breast cancer management

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endocrine (hormone) therapy, and targeted therapy. Research is ongoing for the use of immunotherapy in breast cancer management. Management of breast...

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Breast cancer classification

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Breast cancer classification divides breast cancer into categories according to different schemes criteria and serving a different purpose. The major categories...

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Antineoplastic resistance

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grow despite anti-cancer therapies. In some cases, cancers can evolve resistance to multiple drugs, called multiple drug resistance. There are two general...

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Chemotherapy

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hormones (primarily estrogens for breast cancer and androgens for prostate cancer) are now called hormonal therapies. By contrast, other inhibitions of...

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Metastatic breast cancer

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breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer...

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Palbociclib

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or metastatic breast cancer either in combination with an aromatase inhibitor or, for women who have received prior endocrine therapy, in combination with...

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Somatic evolution in cancer

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tamoxifen resistance". Endocrine-Related Cancer. 11 (4): 643–658. doi:10.1677/erc.1.00776. PMID 15613444. Osborne CK (November 1998). "Tamoxifen in the treatment...

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List of Dove Medical Press academic journals

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and Therapy Biosimilars† Blood and Lymphatic Cancer: Targets and Therapy Botanics: Targets and TherapyBreast Cancer: Targets and Therapy Cancer Management...

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Radiation therapy

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adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation...

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Enzalutamide

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NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells". Endocrine-Related Cancer. 21 (3): 435–42. doi:10.1530/ERC-14-0107...

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Kidney cancer

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syndromes caused by kidney cancer can be broadly classified as endocrine and non-endocrine. Endocrine dysfunctions include increase in blood calcium levels...

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Endometrial cancer

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pus), 10–15% have cancer. Risk factors for endometrial cancer include obesity, insulin resistance and diabetes mellitus, breast cancer, use of tamoxifen...

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Masculinizing hormone therapy

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Masculinizing hormone therapy, also known as transmasculine hormone therapy or female-to-male (or FTM) hormone therapy, is a form of hormone therapy and gender affirming...

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Polycystic ovary syndrome

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syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. The syndrome is named after cysts which...

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Breast development

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"Androgen receptor genotypes predict response to endocrine treatment in breast cancer patients". Br. J. Cancer. 105 (11): 1676–83. doi:10.1038/bjc.2011.441...

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Ovarian cancer

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Hormone therapies are a topic of current research in ovarian cancer, particularly, the value of certain medications used to treat breast cancer. These...

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Acanthosis nigricans

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other areas. It is associated with endocrine dysfunction, especially insulin resistance and hyperinsulinaemia, as seen in diabetes mellitus. This activates...

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Gynecomastia

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2019. Radiation therapy and tamoxifen have been shown to help prevent gynecomastia and breast pain from developing in prostate cancer patients who will...

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Tamoxifen

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lipid effects of endocrine therapy for breast cancer: implications for cardiovascular disease prevention in postmenopausal women". Breast. 15 (3): 301–312...

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