Electrophilic amination is a chemical process involving the formation of a carbon–nitrogen bond through the reaction of a nucleophilic carbanion with an electrophilic source of nitrogen.[1]
^Ciganek, Engelbert (16 March 2009). "Electrophilic Amination of Carbanions, Enolates, and Their Surrogates". Organic Reactions. Vol. 72. John Wiley and Sons, Inc. p. 1–86. doi:10.1002/0471264180.or072.01. ISBN 978-0471264187.
and 25 Related for: Electrophilic amination information
Electrophilicamination is a chemical process involving the formation of a carbon–nitrogen bond through the reaction of a nucleophilic carbanion with...
When the amine is used as an electrophile, the reaction is called electrophilicamination. Electron-rich organic substrates that may be used as nucleophiles...
Reductive amination (also known as reductive alkylation) is a form of amination that involves the conversion of a carbonyl group to an amine via an intermediate...
nitrogen atom and react with a nucleophile as for example in the electrophilicamination of carbanions. Recently, various carbonyls have been turned into...
Individual enantiomers of this compound can be synthesized via electrophilicamination of a chiral oxazolidinone derivative of 3,3-diphenylpropanoic acid...
Chloramine may also aminate nucleophiles (electrophilicamination): Nu− + NH2Cl → NuNH2 + Cl− The amination of ammonia with chloramine to form hydrazine...
The following is the overall form of the general reaction: The direct amination of pyridine with sodium amide takes place in liquid ammonia. Following...
nanotubes have been deposited on with silver nanoparticles with the aid of amination reactions. Amide functionalized carbon nanotubes have been shown to chelate...
carbon. The ease of addition of hydride to the carbonyl is affected by electrophilicity and bulk of the carbonyl as well as the corresponding electronic and...
include alkylation from alkyl halides, arylation from aryl bromides, amination from benzyloxyamines, acylation from anhydrides. Likewise in the case...
occur <pH 7 because the iminium ions are the actual substrates. Reductive amination, sometimes called the Borch reaction, is the conversion of a carbonyl...
Organosilanes, Photochemical protection, Medicinal chemistry, electrophilicamination. Hassner’s group pioneered in methodology for synthesis of small...
benzene, it is electron-rich. It thus participates more rapidly in electrophilic aromatic substitution reactions. Likewise, it is also prone to oxidation:...
Graßl, Simon; Knochel, Paul (28 December 2017). "Cobalt-Catalyzed ElectrophilicAmination of Aryl- and Heteroarylzinc Pivalates with N -Hydroxylamine Benzoates"...
facilitated at the 2-, 4-, and 6-positions but there are only a few examples. Amination and hydroxylation have been observed for substituted pyrimidines. Reactions...
iminium ion (but not the imine itself) formed in situ during a reductive amination reaction is a stronger electrophile than the ketone starting material...
cyclopalladation of aromatic derivatives is usually considered to go through an electrophilic aromatic substitution pathway. The oxidative addition of aryl halides...
reaction that transforms a nitrile into an N-alkyl amide using various electrophilic alkylating reagents. The original reaction formed the alkylating agent...
sulfoxide ligand is thought to promote this step by generating a highly electrophilic, possibly cationic palladium species in situ. This species coordinates...
008.0026. W. Klötzer, J. Stadlwieser, J. Raneburger (1986). "Electrophilic N-Amination of Imide Sodium Salts with O-Diphenylphosphinylhydroxylamine (DPH):...
the most prescribed medications. A tetraiodide, T4, is produced by electrophilic iodination of tyrosine derivative. Synthetic T4 is one of the most heavily...
in homogeneous catalysis. They have proved useful in Buchwald-Hartwig amination and etherification reactions as well as Negishi cross-coupling, Suzuki-Miyaura...
properties of pyridine, as it easily supports bond formation via an electrophilic attack. However, because of the separation of the lone pair from the...
Global Information