Amination is the process by which an amine group is introduced into an organic molecule. This type of reaction is important because organonitrogen compounds are pervasive.
Amination is the process by which an amine group is introduced into an organic molecule. This type of reaction is important because organonitrogen compounds...
Reductive amination (also known as reductive alkylation) is a form of amination that involves the conversion of a carbonyl group to an amine via an intermediate...
The following is the overall form of the general reaction: The direct amination of pyridine with sodium amide takes place in liquid ammonia. Following...
Electrophilic amination is a chemical process involving the formation of a carbon–nitrogen bond through the reaction of a nucleophilic carbanion with...
Transamination is a chemical reaction that transfers an amino group to a ketoacid to form new amino acids.This pathway is responsible for the deamination...
Deamination is the removal of an amino group from a molecule. Enzymes that catalyse this reaction are called deaminases. In the human body, deamination...
Bruyn–van Ekenstein transformation A similar reaction is the so-called Voigt amination where an acyloin reacts with a primary amine and phosphorus pentoxide...
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical...
aldehydes but not most ketones. It is especially suitable for reductive aminations of aldehydes and ketones. However, unlike sodium cyanoborohydride, the...
catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of (R)-MDMA and (S)-MDMA)...
hydrogens (hydrogenolysis). Ammonium formate can be used for reductive amination of aldehydes and ketones (Leuckart reaction), by the following reaction:...
chemical reaction that converts aldehydes or ketones to amines by reductive amination in the presence of heat. The reaction, named after Rudolf Leuckart, uses...
often limited to the synthesis of tertiary amines. An exception is the amination of alpha-halo carboxylic acids that do permit synthesis of primary amines...
This process involves transaminases, often the same as those used in amination during synthesis. In many vertebrates, the amino group is then removed...
scale. Many amines are produced from aldehydes and ketones via reductive amination, which can either proceed catalytically or stoichiometrically. Aniline...
biphenyl. Its palladium complexes exhibit high activity for Buchwald-Hartwig amination reactions involving aryl chlorides and aryl tosylates. Both palladium...
prepared starting from phenylacetone by either the Leuckart or reductive amination methods. In the Leuckart reaction, one equivalent of phenylacetone is...
from ketone-amine mixtures. The conversion is not a genuine reductive amination as only the second half of the two-part reaction is catalyzed. In 2017...
alcohols, aldehydes and ketones can be converted to amines, i.e., reductive amination. Because of its cyano substituent, NaBH3CN is a weak reducer at moderate...
Luo (1986). "Functionalization of polymeric organolithium compounds. Amination of poly(styryl)lithium". Macromolecules. 19 (5): 1291–1294. Bibcode:1986MaMol...
manufactured more conveniently by chemical synthesis. The two main processes are amination of chloroacetic acid with ammonia, giving glycine and ammonium chloride...
catalyst can effect both branched and linear regioselective allylic C-H aminations. In order to promote nucleophilic attack at the internal terminus of the...
Solanaceae plants: Involvement of an aldehyde intermediate during C-26 amination". Phytochemistry. 89: 26–31. Bibcode:2013PChem..89...26O. doi:10.1016/j...
leads to leucine. The intermediate α-ketoisovalerate undergoes reductive amination with glutamate. Enzymes involved in this biosynthesis include: Acetolactate...
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