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Elastase information


Space-filling model of elastase
Crystals of porcine elastase

In molecular biology, elastase is an enzyme from the class of proteases (peptidases) that break down proteins.[1] In particular, it is a serine protease.[2]

  1. ^ Bieth JG (2001). "[The elastases]". J. Soc. Biol. (in French). 195 (2): 173–9. doi:10.1051/jbio/2001195020173. PMID 11723830.
  2. ^ Bruce, Alberts (2014-11-18). Molecular biology of the cell (Sixth ed.). New York, NY. ISBN 9780815344322. OCLC 887605755.{{cite book}}: CS1 maint: location missing publisher (link)

and 26 Related for: Elastase information

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Elastase

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for elastase: Some bacteria (including Pseudomonas aeruginosa) also produce elastase. In bacteria, elastase is considered a virulence factor. Elastase breaks...

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Neutrophil elastase

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Neutrophil elastase (EC 3.4.21.37, leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase, subtype human leukocyte elastase (HLE))...

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Pancreatic elastase

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Pancreatic elastase is a form of elastase that is produced in the acinar cells of the pancreas, initially produced as an inactive zymogen and later activated...

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Macrophage elastase

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Macrophage elastase (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme. This enzyme catalyses the following chemical...

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CELA3B

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Chymotrypsin-like elastase family member 3B also known as elastase-3B, protease E, or fecal elastase is an enzyme that in humans is encoded by the CELA3B...

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Neutrophil

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parasites. In alpha 1-antitrypsin deficiency, the important neutrophil elastase is not adequately inhibited by alpha 1-antitrypsin, leading to excessive...

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Serine protease

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their substrate specificity as either trypsin-like, chymotrypsin-like or elastase-like. Trypsin-like proteases cleave peptide bonds following a positively...

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Pancreatic elastase II

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Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme. This enzyme catalyses the following chemical reaction Preferential cleavage:...

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Elaszym

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Elaszym may refer to one of two enzymes: Pancreatic elastase Neutrophil elastase This disambiguation page lists articles associated with the title Elaszym...

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Exocrine pancreatic insufficiency

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'moderate' EPI is when fecal elastase levels are <200 ug/g, whereas 'severe' EPI is considered to be when fecal elastase levels is <100 ug/g. The exocrine...

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Pseudolysin

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Pseudolysin (EC 3.4.24.26, Pseudomonas elastase, Pseudomonas aeruginosa neutral metalloproteinase) is an enzyme. This enzyme catalyses the following chemical...

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SERPINB1

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Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the SERPINB1 gene. It is a member of the clade B serpins...

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Ecotin

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system, inhibit neutrophil elastase strongly while ecotin from the plant pathogen Pantoea citrea inhibits neutrophil elastase 1000-fold less potently. Ecotins...

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Protease

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Each family may contain many hundreds of related proteases (e.g. trypsin, elastase, thrombin and streptogrisin within the S1 family). Currently more than...

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Elafin

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protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific protease inhibitor, which contains a WAP-type four-disulfide core...

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SLPI

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seminal fluids. SLPI inhibits human leukocyte elastase, human cathepsin G, human trypsin, neutrophil elastase, and mast cell chymase. X-ray crystallography...

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Type 3c diabetes

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Presence of exocrine pancreatic insufficiency (according to monoclonal fecal elastase-1 or direct function tests). Pathological pancreatic imaging: (by endoscopic...

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Azurophilic granule

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Azurophils may contain myeloperoxidase, phospholipase A2, acid hydrolases, elastase, defensins, neutral serine proteases, bactericidal permeability-increasing...

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Smegma

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Littré. Smegma contains cathepsin B, lysozymes, chymotrypsin, neutrophil elastase and cytokines, which aid the immune system. According to Wright, the production...

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Aspergillus fumigatus

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amount of elastase production and tissue invasion was first discovered in 1984. Clinical isolates have also been found to have greater elastase activity...

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Abdominal aortic aneurysm

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induced) and the elastase model (non-dissecting, chemically induced model). A recent study has shown that β-Aminopropionitrile plus elastase application to...

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Oleanolic acid

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Oleanolic acid is also used as standard for comparison of hyaluronidase, elastase and matrix-metalloproteinase-1 inhibition of other substances in primary...

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Chronic obstructive pulmonary disease

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breakdown of the connective tissue of the lungs by proteases (particularly elastase) that are insufficiently inhibited by protease inhibitors. The destruction...

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Ilona Banga

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contraction. She and her husband József Mátyás Baló discovered the first elastase – an enzyme capable of degrading the protein elastin which gives tissues...

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Neutropenia

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mostly caused by heterozygous mutations in the ELANE gene (neutrophil elastase). Neutropenia can be acute (temporary) or chronic (long lasting). The term...

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Hair loss

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response involves the proteolysis of type XVII collagen by neutrophil elastase in response to DNA damage in hair follicle stem cells. Proteolysis of collagen...

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