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EIF4B information


EIF4B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF4B, EIF-4B, PRO1843, eukaryotic translation initiation factor 4B
External IDsOMIM: 603928; MGI: 95304; HomoloGene: 83162; GeneCards: EIF4B; OMA:EIF4B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300821
NM_001417
NM_018507
NM_001330654

NM_145625

RefSeq (protein)

NP_001287750
NP_001317583
NP_001408

NP_663600

Location (UCSC)Chr 12: 53.01 – 53.04 MbChr 15: 101.98 – 102.01 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000063046 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058655 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: EIF4B eukaryotic translation initiation factor 4B".

and 20 Related for: EIF4B information

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EIF4B

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initiation factor 4B is a protein that in humans is encoded by the EIF4B gene. eIF4B has been shown to interact with and stimulate the activity of eIF4A...

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Eukaryotic initiation factor 4F

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trimer, the eIF4F complex functionally interacts with proteins including eIF4B and eIF4H. The unusual isoform of eIF4G, eIF4G2 or DAP5, also appears to...

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MTORC1

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A (eIF4A) and its cofactor eukaryotic translation initiation factor 4B (eIF4B). The helicase is required to remove hairpin loops that arise in the 5'...

Word Count : 7803

Eukaryotic initiation factor

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subunit has multiple human isoforms and there exist additional eIF4 proteins: eIF4B and eIF4H. eIF4G is a 175.5-kDa scaffolding protein that interacts with...

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Stress granule

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Factor 4A2 EIF4A3 EIF4A3 Eukaryotic Translation Initiation Factor 4A3 EIF4B EIF4B Eukaryotic translation Initiation factor 4B EIF4E EIF4E Eukaryotic Translation...

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KIAA2013

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image. Most miRNA seem to congregate around the two conserved domains. EIF4B is known as eukaryotic translation initiation factor 4B and is needed to...

Word Count : 1669

Eukaryotic initiation factor 3

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connection. However, both mammalian and yeast eIF3 independently bind eIF1, eIF4B, and eIF5. Several subunits of eIF3 contain RNA recognition motifs (RRMs)...

Word Count : 2101

Hepatitis C virus internal ribosome entry site

Last Update:

translation, as are components of the eIF4F complex (eIF4A, eIF4E, and eIF4G) and eIF4B, which are generally required for mRNA binding and unwinding of 5'UTR. Initiator...

Word Count : 481

EIF1

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40S subunit in order to induce DEAD-box RNA helicase eIF4A, its cofactor eIF4B, and eIF4G activity.    Eukaryotic initiation factors GRCh38: Ensembl release...

Word Count : 828

EIF4A

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proteins are referred to as eIF4F. For maximal activity; eIF4A also requires eIF4B (80 kDa), which itself is enhanced by eIF4H (25 kDa). A study conducted...

Word Count : 1828

EIF4A1

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considerably improves in the presence of eIF4B and eIF4H, binding partners that modulate its activity. When eIF4B binds to eIF4A1, the helicase activity...

Word Count : 2579

RPS6KB2

Last Update:

the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell...

Word Count : 993

SR protein

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of the mTOR pathway. SF2/ASF increases the phosphorylation of rpS6 and eIF4B by S6K1. 9G8 increases the translation of unspliced mRNA with a constitutive...

Word Count : 3445

EIF4H

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virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H". J Virol. 78 (9): 4684–99. doi:10.1128/JVI.78.9.4684-4699.2004...

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YIF1A

Last Update:

respectively. The 5' untranslated region has predicted sites for binding by RBXM, EIF4B, and FUS. The 3' untranslated region has predicted sites for binding by...

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FAM208b

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binding proteins RBMX1, FUS, SFRS1, ACO1, and NONO. The 3' UTR is bound by EIF4B, A2BP1, and ZFP36. A single non-coding variant of FAM208b is transcribed...

Word Count : 2213

EIF3A

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EIF3C, EIF3D, EIF3EIP, EIF3F, EIF3G, EIF3H, EIF3I EIF3J, EIF3K, EIF3S6, EIF4B, EIF4G2, and FBXO32. Eukaryotic initiation factor 3 (eIF3) GRCh38: Ensembl...

Word Count : 1367

FANCD2OS

Last Update:

The sequence for the secondary structure of the 3’ UTR are recognized by EIF4B and RBMX. FANCD2OS is moderately expressed in the human brain, placenta...

Word Count : 375

RNA recognition motif

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D10S102; DAZ1; DAZ2; DAZ3; DAZ4; DAZAP1; DAZL; DNAJC17; DND1; EIF3S4; EIF3S9; EIF4B; EIF4H; ELAVL1; ELAVL2; ELAVL3; ELAVL4; ENOX1; ENOX2; EWSR1; FUS; FUSIP1;...

Word Count : 812

SMIM19

Last Update:

complex involved on pre-mRNA splicing and export of mRNA to the cytoplasm EIF4B eukaryotic translation factor 4B 8.05 88% 431-437 GCGGAAA Protein required...

Word Count : 2273

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