The extracellular core region containing desmocollin and desmoglein, and the plaque contain desmoplakin, which attaches to keratin intermediate filaments. Desmosome is a intercellular junction in animal cell.
Details
Identifiers
Latin
Desmosoma Macula adhaerens
MeSH
D003896
TH
H1.00.01.1.02015
FMA
67412
Anatomical terminology
[edit on Wikidata]
A desmosome (/ˈdɛzməˌsoʊm/;[1][2] "binding body"), also known as a macula adherens (plural: maculae adherentes) (Latin for adhering spot), is a cell structure specialized for cell-to-cell adhesion. A type of junctional complex, they are localized spot-like adhesions randomly arranged on the lateral sides of plasma membranes. Desmosomes are one of the stronger cell-to-cell adhesion types and are found in tissue that experience intense mechanical stress, such as cardiac muscle tissue, bladder tissue, gastrointestinal mucosa, and epithelia.[3]
^"Desmosome". Lexico UK English Dictionary. Oxford University Press. Archived from the original on 2020-01-27.
^Delva, Emmanuella; Tucker, Dana K.; Kowalczyk, Andrew P. (August 2009). "The desmosome". Cold Spring Harbor Perspectives in Biology. 1 (2): a002543. doi:10.1101/cshperspect.a002543. ISSN 1943-0264. PMC 2742091. PMID 20066089.
A desmosome (/ˈdɛzməˌsoʊm/; "binding body"), also known as a macula adherens (plural: maculae adherentes) (Latin for adhering spot), is a cell structure...
vertebrates, there are three major types of cell junction: Adherens junctions, desmosomes and hemidesmosomes (anchoring junctions) Gap junctions (communicating...
possess the cell junctions called tight junctions, gap junctions, and desmosomes. With few exceptions—in particular, the sponges and placozoans—animal...
microfilaments. Desmosomes attach to the microfilaments of cytoskeleton made up of keratin protein. Hemidesmosomes resemble desmosomes on a section. They...
adherens junctions (or zonula adherens, intermediate junction, or "belt desmosome") are protein complexes that occur at cell–cell junctions and cell–matrix...
which form the thick cytoplasmic plaques in desmosomes and link cadherins to intermediate filaments. Desmosomes provides strength and resistance to mechanical...
types of cell junction recognised as making up an intercalated disc are desmosomes, fascia adherens junctions, and gap junctions. Fascia adherens are anchoring...
of the cardiac muscle known as desmosomes, areas on the surface of muscle cells which link them together. The desmosomes are composed of several proteins...
These are joined with desmosomes. Their spiny (Latin, spinosum) appearance is due to shrinking of the microfilaments between desmosomes that occurs when stained...
extracellular matrix. They are similar in form to desmosomes when visualized by electron microscopy, however, desmosomes attach to adjacent cells. Hemidesmosomes...
structures such as caveolae, postsynaptic density, podosome, invadopodium, desmosome, hemidesmosome, focal adhesion, and cell junctions. These types of membranes...
the cell against physical stress. It does this through connections to desmosomes, cell–cell junctional plaques, and hemidesmosomes, cell-basement membrane...
keratinocytes will become highly organized, forming cellular junctions (desmosomes) between each other and secreting keratin proteins and lipids which contribute...
junction which can be identified at the ultrastructural level: Gap junctions Desmosomes Adherens junctions Tight junctions Gap junctions bring the adjacent cells...
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, seen in diseases such as...
that is encoded by the DSP gene. Desmoplakin is a critical component of desmosome structures in cardiac muscle and epidermal cells, which function to maintain...
Proteolysis of the peptide bond leading up to the dysfunction of Dsg1 and the desmosome allows for an understanding as to why the bullous forms, making the peptide...
attached to each other and to the overlying stratum spinosum cells by desmosomes and hemidesmosomes. The nucleus is large, ovoid and occupies most of the...
are formed against desmosomes, components of the skin that function to keep certain layers of skin bound to each other. As desmosomes are attacked, the...
spinous layer (stratum spinosum) Keratinocytes become connected through desmosomes and produce lamellar bodies, from within the Golgi, enriched in polar...
contributes to the skin's barrier function. Corneodesmosomes (modified desmosomes) facilitate cellular adhesion by linking adjacent cells within this epidermal...
anchoring fascia adherens junctions, the intermediate filament anchoring desmosomes, and gap junctions. They allow action potentials to spread between cardiac...
"glue" that attaches adjacent epidermal cells via attachment points called desmosomes. When autoantibodies attack desmogleins, the cells become separated from...
playing a role in some cell functions. In combination with proteins and desmosomes, the intermediate filaments form cell-cell connections and anchor the...
to each other by intercalated disks, which contain gap junctions and desmosomes. Unlike skeletal and cardiac muscle tissue, smooth muscle tissue is not...
sarcomeres in muscle cells and connect different cell organells like the desmosomes with the cytoskeleton. Glial fibrillary acidic protein (GFAP) is found...
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