Typical "owl eye" intranuclear inclusion indicating CMV infection of a lung pneumocyte[1]
Virus classification
(unranked):
Virus
Realm:
Duplodnaviria
Kingdom:
Heunggongvirae
Phylum:
Peploviricota
Class:
Herviviricetes
Order:
Herpesvirales
Family:
Orthoherpesviridae
Subfamily:
Betaherpesvirinae
Genus:
Cytomegalovirus
Species
See text
Synonyms[2]
Human cytomegalovirus group
Cytomegalovirus (CMV) (from cyto- 'cell' via Greek κύτοςkútos- 'container' + μέγαςmégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae,[3] in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts. The 11 species in this genus include human betaherpesvirus 5 (HCMV, human cytomegalovirus, HHV-5), which is the species that infects humans. Diseases associated with HHV-5 include mononucleosis and pneumonia,[4][5] and congenital CMV in infants can lead to deafness and ambulatory problems.[6]
In the medical literature, most mentions of CMV without further specification refer implicitly to human CMV. Human CMV is the most studied of all cytomegaloviruses.[7]
MX2/MXB was identified as a restriction factor for herpesviruses, which acts at a very early stage of the replication cycle and MX2/MXB restriction of herpesvirus requires GTPase activity.[8]
^Mattes FM, McLaughlin JE, Emery VC, Clark DA, Griffiths PD (August 2000). "Histopathological detection of owl's eye inclusions is still specific for cytomegalovirus in the era of human herpesviruses 6 and 7". Journal of Clinical Pathology. 53 (8): 612–4. doi:10.1136/jcp.53.8.612. PMC 1762915. PMID 11002765.
^Francki RI, Fauquet CM, Knudson DL, Brown (1991). "Classification and nomenclature of viruses. Fifth Report of the International Committee on Taxonomy of Viruses" (PDF). Arch. Virol.: 107.
^Anshu A, Tan D, Chee SP, Mehta JS, Htoon HM (August 2017). "Interventions for the management of CMV-associated anterior segment inflammation". The Cochrane Database of Systematic Reviews. 2017 (8): CD011908. doi:10.1002/14651858.cd011908.pub2. PMC 6483705. PMID 28838031.
^"Viral Zone". ExPASy. Retrieved 15 June 2015.
^"Virus Taxonomy: 2022 Release". International Committee on Taxonomy of Viruses (ICTV). March 2023. Retrieved 16 September 2022.
^"Often overlooked, a common infection during pregnancy kickstarts a conversation about newborn screening". STAT. 5 April 2023. Retrieved 5 April 2023.
^Ryan KJ, Ray CG, eds. (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 556, 566–9. ISBN 978-0-8385-8529-0.
^Staeheli P, Haller O (December 2018). "Human MX2/MxB: a Potent Interferon-Induced Postentry Inhibitor of Herpesviruses and HIV-1". Journal of Virology. 92 (24). doi:10.1128/JVI.00709-18. PMC 6258936. PMID 30258007.
A Cytomegalovirus vaccine is a vaccine to prevent cytomegalovirus (CMV) infection or curb virus re-activation (symptomatic flare-ups) in persons already...
vision Blind spots Specks in your vision Cytomegalovirus (a type of herpes virus) is what causes cytomegalovirus retinitis. Other types of herpes viruses...
betaherpesvirus 5, also called human cytomegalovirus (HCMV,HHV-5), is a species of virus in the genus Cytomegalovirus, which in turn is a member of the viral...
with cytomegalovirus by the time they reach adulthood, but most are unaware of the infection. Once a person becomes infected with cytomegalovirus, the...
Cytomegalovirus papiinebeta4, formerly Papiine betaherpesvirus 4 (PaHV-4), is a species of virus in the genus Cytomegalovirus, subfamily Betaherpesvirinae...
Cytomegalovirus colitis (CMV colitis) is an inflammation of the colon. The infection is spread by saliva, urine, respiratory droplets, sexual contact...
Cytomegalovirus esophagitis is a form of esophagitis associated with cytomegalovirus. Symptoms include dysphagia, upper abdominal pain, diarrhea, nausea...
several diseases, including mononucleosis and some cancers), and human cytomegalovirus (HCMV or HHV-5). More than 90% of adults have been infected with at...
post-transplant cytomegalovirus (CMV). Maribavir is a cytomegalovirus pUL97 kinase inhibitor that works by preventing the activity of human cytomegalovirus enzyme...
are also of interest as a therapeutic target for treatment of human cytomegalovirus. The earliest identified and best characterized IEGs include c-fos...
herpes simplex or herpes zoster (shingles). It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. It is taken by mouth...
condition can occur following infection of an unborn baby with rubella, cytomegalovirus, toxoplasmosis, or coxsackie virus. Other viral causes include parvovirus...
family Bromoviridae Cytomegalovirus, a genus in the family Herpesviridae Human cytomegalovirus, a human-infecting species of cytomegalovirus commonly known...
For the treatment of viral haemorrhagic fevers For the treatment of cytomegalovirus retinitis (CMVr). For severe illness due to confirmed or suspected...
greatly reduces the time to detection for slow growing viruses such as cytomegalovirus, for which the method was developed. In addition, the centrifugation...
(2008). "Modulation of Host Cell Stress Responses by Human Cytomegalovirus". Human Cytomegalovirus. Current Topics in Microbiology and Immunology. Vol. 325...
name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections. Ganciclovir was patented in 1980 and approved for...
chromatin compacts (becomes latent) upon oxygen and nutrient deprivation. Cytomegalovirus (CMV) establishes latency in myeloid progenitor cells, and is reactivated...
Laureate and research pioneer in poliomyelitis, varicella-zoster virus, cytomegalovirus, rubella, and other infectious diseases". Seminars in Pediatric Infectious...
Shingles Yellow fever# combination: Hepatitis A and B MMR MMRV research: Cytomegalovirus Dengue# Epstein–Barr virus Hepatitis C Herpes simplex HIV Zika Protozoan...
A transfusion transmitted infection (TTI) is a virus, parasite, or other potential pathogen that can be transmitted in donated blood through a transfusion...
be associated with TM include HIV, herpes simplex, herpes zoster, cytomegalovirus, and Epstein-Barr. Flavivirus infections such as Zika virus and West...
focused on genetically limited versions of the virus.[citation needed] Cytomegalovirus (CMV) is part of the β-herpesvirus subfamily that includes roseoloviruses...
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