The enzyme cyanide hydratase (EC 4.2.1.66) catalyzes the chemical reaction
formamide cyanide + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is formamide hydro-lyase (cyanide-forming). Other names in common use include formamide dehydratase, and formamide hydro-lyase.[1] This enzyme participates in cyanoamino acid metabolism.
^Gupta, Neha; Balomajumder, Chandrajit; Agarwal, V. K. (2010-04-15). "Enzymatic mechanism and biochemistry for cyanide degradation: A review". Journal of Hazardous Materials. 176 (1): 1–13. doi:10.1016/j.jhazmat.2009.11.038. ISSN 0304-3894.
The enzyme cyanidehydratase (EC 4.2.1.66) catalyzes the chemical reaction formamide ⇌ {\displaystyle \rightleftharpoons } cyanide + H2O This enzyme belongs...
group are not called nitriles, but cyanides instead. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly...
unstable and could lead to the formation of cyanide via different transformations. For example, via epoxide hydratase (EH) or via interactions with a sulfhydryl...
be confused with nitrile hydratase (nitrile hydro-lyase; EC 4.2.1.84) which hydrolyses nitriles to amides. Nitrile hydratases are almost invariably co-expressed...
Myrothecium verrucaria, accelerate this process utilizing the enzyme cyanamide hydratase. Cyanamide is the name for a functional group with the formula R1R2N−C≡N...
oxidized in a separate reactor with nitric acid. The enzyme Acetylene hydratase discovered in the strictly anaerobic bacterium Pelobacter acetylenicus...
bacteria living on acetylene have been identified. The enzyme acetylene hydratase catalyzes the hydration of acetylene to give acetaldehyde: C2H2 + H2O...
used in enzymes due to its Lewis acid properties, for example in nitrile hydratase. Iron is frequently found in mononuclear sites in the reduced Fe(II) form...
Selak MA, Gottlieb E (August 2006). "Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer". Oncogene. 25 (34): 4675–4682...
the amides. Fe- and Co-nitrile complexes are intermediates in nitrile hydratase enzymes. N-coordination activates the sp-hybridized carbon center toward...
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