(Kinoshita et al. 1958) Abe et al. 1967 (Approved Lists 1980)
Synonyms[1][2]
Brevibacterium divaricatum Su and Yamada 1960 (Approved Lists 1980)
"Brevibacterium flavum" Okumura et al. 1962
Corynebacterium lilium Lee and Good 1963 (Approved Lists 1980)
"Micrococcus glutamicus" Kinoshita et al. 1958
Corynebacterium glutamicum is a Gram-positive, rod-shaped bacterium that is used industrially for large-scale production of amino acids,[3][4] especially glutamic acid and lysine.[5] While originally identified in a screen for organisms secreting L-glutamate, mutants of C. glutamicum have also been identified that produce various other amino acids and derivatives of amino acids.[6]
Due to its industrial importance, several clones of C. glutamicum have been sequenced by both industry and academic groups.[5] Furthermore, small RNA data was obtained by RNA-Seq in C. glutamicum ATCC 13032.[7] The metabolism of this strain has been reconstructed and is available in the form of a genome-scale metabolic model.[8]
^Tatsumi, Nami; Inui, Masayuki (14 August 2012). Corynebacterium glutamicum: Biology and Biotechnology. Springer Science & Business Media. p. 336. ISBN 978-3-642-29857-8.
^Lv, Yangyong; Juanjun, Liao; Wu, Zhanhong; et al. (February 2012). "Genome Sequence of Corynebacterium glutamicum ATCC 14067, Which Provides Insight into Amino Acid Biosynthesis in Coryneform Bacteria". Journal of Bacteriology. 194 (3): 742–743. doi:10.1128/JB.06514-11. PMC 3264075. PMID 22247536.
^Kinoshita, Shukuo; Udaka, Shigezo; Shimono, Masakazu (1957), "Studies on the amino acid fermentation. Part 1. Production of L-glutamic acid by various microorganisms", Journal of General and Applied Microbiology, 3 (3): 193–205, doi:10.2323/jgam.3.193, PMID 15965888{{citation}}: CS1 maint: multiple names: authors list (link)
^Udaka, Shigezo (1960), "Screening method for microorganisms accumulating metabolites and its use in the isolation of Micrococcus glutamicus", Journal of Bacteriology, 79 (5): 754–755, doi:10.1128/jb.79.5.754-755.1960, PMC 278770, PMID 13840150
^ abKalinowski, J; Bathe, B; Bartels, D; et al. (4 September 2003). "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of l-aspartate-derived amino acids and vitamins". Journal of Biotechnology. 104 (1–3): 5–25. doi:10.1016/S0168-1656(03)00154-8. PMID 12948626.
^Zahoor A; Lindner SN; Wendisch VF (October 2012). "Metabolic Engineering of Corynebacterium glutamicum Aimed at Alternative Carbon Sources and New Products". Computational and Structural Biotechnology Journal. 3 (4): e201210004. doi:10.5936/csbj.201210004. PMC 3962153. PMID 24688664.
^Mentz, Almut; Neshat, Armin; Pfeifer-Sancar, Katharina; et al. (2013-10-19). "Comprehensive discovery and characterization of small RNAs in Corynebacterium glutamicum ATCC 13032". BMC Genomics. 14 (1): 714. doi:10.1186/1471-2164-14-714. ISSN 1471-2164. PMC 4046766. PMID 24138339.
^Feierabend, Martina; Renz, Alina; Zelle, Elisabeth; et al. (2021). "High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032". Frontiers in Microbiology. 12 (10): 3432. doi:10.3389/fmicb.2021.750206. ISSN 1664-302X. PMC 8634658. PMID 34867870.
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Corynebacteriumglutamicum is a Gram-positive, rod-shaped bacterium that is used industrially for large-scale production of amino acids, especially glutamic...
mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacteriumglutamicum as a model of Emb proteins of Mycobacterium tuberculosis". Glycobiology...
species of the gram-positive Corynebacterium are used for the commercial production of various amino acids. The C. glutamicum species is widely used for...
biosynthesis, its regulation and biotechnological application in Corynebacteriumglutamicum". Microbial Biotechnology. 7 (1): 5–25. doi:10.1111/1751-7915...
commerically used metabolites with are produced by microorganisms. Corynebacteriumglutamicum is one of the most important bacterial species with an annual...
The industrial process includes the fermentative culturing of Corynebacteriumglutamicum and the subsequent purification of lysine. Good sources of lysine...
meats. Manufacturers, such as Ajinomoto, use selected strains of Corynebacteriumglutamicum bacteria in a nutrient-rich medium. The bacteria are selected...
proteins in Corynebacteriumglutamicum and Corynebacterium efficiens". In Eggeling, Lothar; Bott, Michael (eds.). Handbook of Corynebacteriumglutamicum. CRC...
"High-Level Production of the Natural Blue Pigment Indigoidine from Metabolically Engineered Corynebacteriumglutamicum for Sustainable Fabric Dyes" v t e...
of bacteria, including Bacillus subtilis, Escherichia coli and Corynebacteriumglutamicum. It is notable for containing a riboswitch, a structure in its...
succiniciproducens or genetically modified Escherichia coli, Corynebacteriumglutamicum and Saccharomyces cerevisiae. Understanding of the central carbon...
(2005-09-01). "E1 Enzyme of the Pyruvate Dehydrogenase Complex in Corynebacteriumglutamicum: Molecular Analysis of the Gene and Phylogenetic Aspects". Journal...
biosynthesis, its regulation and biotechnological application in Corynebacteriumglutamicum". Microbial Biotechnology. 7 (1): 5–25. doi:10.1111/1751-7915...
(2012). "Bio-based production of chemicals, materials and fuels -Corynebacteriumglutamicum as versatile cell factory". Current Opinion in Biotechnology....
of divalent cation dependent decarboxylases was isolated from Corynebacteriumglutamicum in 1995 by Jetten et al. This enzyme selectively catalyzed the...
fermentation of sugars and ammonia in the 1950s, with the organism Corynebacteriumglutamicum (also known as Brevibacterium flavum) being the most widely used...
The production of these amino acids is due to Corynebacteriumglutamicum and fermentation. C.glutamicum was engineered to be able to produce L-lysine...
following: (i) Identification of constraints to lysine production in Corynebacteriumglutamicum and insertion of new genes to relieve these constraints to improve...
named based on the early discovery of the LysE carrier protein of Corynebacteriumglutamicum. 2.A.75 - The L-Lysine Exporter (LysE) Family 2.A.76 - The Resistance...
divergent species. Characterized LIV-E transporters include BrnFE in Corynebacteriumglutamicum, AzlCD in Bacillus subtilis, and YgaZH in Escherichia coli.. The...
2000). "A highly specific monomeric isocitrate dehydrogenase from Corynebacteriumglutamicum". Archives of Biochemistry and Biophysics. 383 (2): 238–245. doi:10...
C are cell wall channel-forming proteins from Corynebacterium. Porin B from Corynebacteriumglutamicum (Brevibacterium flavum) allows the exchange of...
racemization process. Beet sugar molasses, with a Corynebacterium (especially Corynebacteriumglutamicum) and combined with penicillin or a surfactant to...
rolling circle replication to maintain a low copy number. In Corynebacteriumglutamicum, it achieves this by antisense pairing with the mRNA of RepB,...
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