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Clonally transmissible cancer information


A transmissible cancer is a cancer cell or cluster of cancer cells that can be transferred between individuals without the involvement of an infectious agent, such as an Oncovirus.[1][2] The evolution of transmissible cancer has occurred naturally in other animal species, but human cancer transmission is rare.[2] This transfer is typically between members of the same species or closely related species.[3]

  1. ^ Ostrander EA, Davis BW, Ostrander GK (January 2016). "Transmissible Tumors: Breaking the Cancer Paradigm". Trends in Genetics. 32 (1): 1–15. doi:10.1016/j.tig.2015.10.001. PMC 4698198. PMID 26686413.
  2. ^ a b Welsh JS (2011). "Contagious cancer". The Oncologist. 16 (1): 1–4. doi:10.1634/theoncologist.2010-0301. PMC 3228048. PMID 21212437.
  3. ^ Dujon AM, Gatenby RA, Bramwell G, MacDonald N, Dohrmann E, Raven N, et al. (July 2020). "Transmissible Cancers in an Evolutionary Perspective". iScience. 23 (7): 101269. Bibcode:2020iSci...23j1269D. doi:10.1016/j.isci.2020.101269. PMC 7327844. PMID 32592998.

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Plasmodium in nature and most populations of parasitic protists may be clonal lines that rarely exchange genes with other members of their species. The...

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with pregnancies and only a marginal few organ donors, cancer is generally not a transmissible disease. The main reason for this is tissue graft rejection...

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Cancer

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JK, Kim SY, Fassati A, Weiss RA (August 2006). "Clonal origin and evolution of a transmissible cancer". Cell. 126 (3): 477–87. doi:10.1016/j.cell.2006...

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chromosomally distinct episomes in cancer cells, where the viruses express oncogenes that promote cancer cell proliferation. In cancers, these episomes passively...

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vaccines since their discovery in the 18th century. Some medicines such as the cancer drug trabectedin are based on toxins or other molecules of animal origin...

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known transmissible cancers in mammals; the others are devil facial tumor disease, a cancer which occurs in Tasmanian devils, and canine transmissible venereal...

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established cause of cancer in humans and other species. Viral cancers occur only in a minority of infected persons (or animals). Cancer viruses come from...

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Non-cellular life Comparable structures Bio-like structure Cancer cell HeLa Clonally transmissible cancer Cosmid Defective interfering particle Endogenous viral...

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Life

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the remainder of the organism for survival. Such organisms are formed clonally or from a single germ cell that is capable of forming the various specialised...

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intermittent porphyria (AIP). Predisposition to cancer LINE1(L1) TE's and other retrotransposons have been linked to cancer because they cause genomic instability...

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Cell division

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effects such as age-related diseases and shortened lifespans in humans. Cancer cells, on the other hand, are not thought to degrade in this way, if at...

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Devil facial tumour disease

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non-viral clonally transmissible cancer which affects Tasmanian devils, a marsupial native to the Australian island of Tasmania. The cancer manifests...

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lead to multiple clinical disorders including neurological disorders and cancer. Unlike the outer membrane, the inner membrane does not contain porins,...

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plants had been budded—indicating that the disease was caused by a transmissible pathogenic agent. A fungus or bacterium could not be found consistently...

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Cosmid

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hybrid plasmid that contains a Lambda phage cos sequence. Often used as cloning vectors in genetic engineering, cosmids can be used to build genomic libraries...

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