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Chromosome territories information


The 23 human chromosome territories during prometaphase in fibroblast cells

In cell biology, chromosome territories are regions of the nucleus preferentially occupied by particular chromosomes.

Interphase chromosomes are long DNA strands that are extensively folded, and are often described as appearing like a bowl of spaghetti. The chromosome territory concept holds that despite this apparent disorder, chromosomes largely occupy defined regions of the nucleus.[1] Most eukaryotes are thought to have chromosome territories, although the budding yeast S. cerevisiae is an exception to this.[2]

  1. ^ Meaburn, Misteli T (January 25, 2007). "Chromosome territories". Nature. 445 (7126): 379–781. doi:10.1038/445379a. PMID 17251970. S2CID 4426363.
  2. ^ Cremer T, Cremer M (March 2010). "Chromosome Territories". Cold Spring Harb Perspect Biol. 2 (3): a003889. doi:10.1101/cshperspect.a003889. PMC 2829961. PMID 20300217.

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Chromosome territories

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cell biology, chromosome territories are regions of the nucleus preferentially occupied by particular chromosomes. Interphase chromosomes are long DNA...

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Chromosome

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A chromosome is a package of DNA with part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated...

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Nuclear organization

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distinct properties. Moreover, entire chromosomes segregate into distinct regions called chromosome territories. Each human cell contains around two metres...

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X chromosome

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The X chromosome is one of the two sex chromosomes in many organisms, including mammals, and is found in both males and females. It is a part of the XY...

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Homologous chromosome

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A pair of homologous chromosomes, or homologs, is a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization...

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Cell nucleus

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individual patches, called chromosome territories. Active genes, which are generally found in the euchromatic region of the chromosome, tend to be located towards...

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Barr body

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X-chromatin is an inactive X chromosome. In species with XY sex-determination (including humans), females typically have two X chromosomes, and one is rendered...

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Chromosome 19

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Chromosome 19 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 19 spans more than 61.7...

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Chromosome conformation capture

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In 1975, Pierre Chambon coined the term nucleosomes. In 1982, Chromosome territories were discovered. In 1984, John T. Lis innovated the Chromatin immunoprecipitation...

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DNA

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different chromosomes even occupy separate areas in the nucleus called "chromosome territories". This physical separation of different chromosomes is important...

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Condensin

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Condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis (Figure 1). Their subunits...

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Thomas Cremer

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and aberrant chromosomes and chromosomal subregions directly in the cell nucleus and provided direct evidence for chromosome territories (CTs). During...

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Euchromatin

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(October 1999). "Spatial relationship between transcription sites and chromosome territories". The Journal of Cell Biology. 147 (1): 13–24. doi:10.1083/jcb.147...

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Genomics

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"Rise, fall and resurrection of chromosome territories: a historical perspective. Part I. The rise of chromosome territories". European Journal of Histochemistry...

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Topologically associating domain

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preferentially contact each other. They were discovered in 2012 using chromosome conformation capture techniques including Hi-C. They have been shown to...

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Fluorescence in situ hybridization

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DNA sequences on chromosomes. Fluorescence microscopy can be used to find out where the fluorescent probe is bound to the chromosomes. FISH is often used...

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Chromatin

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interphase chromosomes forming chromosome territories would result in formation of highly knotted chromatin fibres. However, Chromosome Conformation Capture (3C)...

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Nuclear matrix

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arguments that the relative position of chromosome territories (CTs), the equivalent of condensed metaphase chromosomes at interphase, may be maintained due...

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Cajal body

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PMC 2173504. PMID 12379800. Cremer T, Cremer C (April 2001). "Chromosome territories, nuclear architecture and gene regulation in mammalian cells". Nature...

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Theodor Boveri

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PMID 14775717. S2CID 4189392. Cremer, Thomas; Cremer, Marion (2010). "Chromosome Territories". Cold Spring Harbor Perspectives in Biology. 2 (3): a003889. doi:10...

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Replication timing

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along the length of a chromosome are duplicated. In eukaryotic cells (cells that package their DNA within a nucleus), chromosomes consist of very long...

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Christoph Cremer

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genome structure research (establishing the existence of so-called chromosome territories in living mammalian cells) and led, a few years later (1979/1980)...

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Homologous somatic pairing

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interchromosomal interactions such as looping, and organisation into chromosomal territories). While meiotic pairing has been extensively studied, the role...

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Vole

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unusual chromosomal traits. Species have been found with 17 to 64 chromosomes. In some species, males and females have different chromosome numbers,...

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Demographics of India

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on Population List of states and union territories of India by population List of states and union territories of India by fertility rate List of Indian...

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Muntjac

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mammal with the lowest recorded chromosome number: The male has a diploid number of 7, the female only 6 chromosomes. Reeves's muntjac (M. reevesi), in...

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Jackal

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large carnivores that are genetically closely related. They all have 78 chromosomes. The group includes genus Canis, Cuon, and Lycaon. The members are the...

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