Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm.
Condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis (Figure 1).[1][2] Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts.[3]
^Hirano T (2016). "Condensin-based chromosome organization from bacteria to vertebrates". Cell. 164 (5): 847–857. doi:10.1016/j.cell.2016.01.033. PMID 26919425.
^Kalitsis P, Zhang T, Marshall KM, Nielsen CF, Hudson DF (2017). "Condensin, master organizer of the genome". Chromosome Res. 25 (1): 61–76. doi:10.1007/s10577-017-9553-0. PMID 28181049. S2CID 28241964.
^Hirano T, Kobayashi R, Hirano M (1997). "Condensins, chromosome condensation complex containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein". Cell. 89 (4): 511–21. doi:10.1016/S0092-8674(00)80233-0. PMID 9160743. S2CID 15061740.
different types of condensin complexes, known as condensin I and condensin II, each of which is composed of five subunits (Figure 2). Condensins I and II share...
identified as the main components of the scaffold: DNA topoisomerase IIα, condensins, and the KIF4A kinesin. When these proteins are removed, the chromosome...
core of the condensin complexes implicated in chromosome condensation. SMC2 and SMC4 have the function of DNA repair as well. Condensin I plays a role...
ten-thousand-fold. The chromosome scaffold, which is made of proteins such as condensin, TOP2A and KIF4, plays an important role in holding the chromatin into...
non-SMC regulatory proteins to form condensin. In condensin I, SMC2 complexes with CAP-H, CAP-D2, and CAP-G. In condensin II, SMC2 complexes with CAP-H2,...
that in humans is encoded by the SMC4 gene. SMC-4 is a core subunit of condensin I and II, large protein complexes involved in high order chromosome organization...
order structures. Chromosome scaffolds are made of proteins including condensin, type IIA topoisomerase and kinesin family member 4 (KIF4). The physical...
in mitosis can be attributed to the inactivation of topoisomerase II, condensin, or separase. Meiotic nondisjunction has been well studied in Saccharomyces...
sister DNAs are segregated into daughter cells. It has been shown that condensin, a large protein complex that plays a central role in mitotic chromosome...
Cohesin is a member of the SMC family of protein complexes which includes Condensin, MukBEF and SMC-ScpAB. Cohesin was separately discovered in budding yeast...
Condensin complex subunit 2 also known as chromosome-associated protein H (CAP-H) or non-SMC condensin I complex subunit H (NCAPH) is a protein that in...
"Multiscale Structuring of the E. coli Chromosome by Nucleoid-Associated and Condensin Proteins". Cell. 172 (4): 771–783.e18. doi:10.1016/j.cell.2017.12.027...
lengths reaching 0.7 μm down to 0.2-0.3 μm. This process employs the condensin complex. Condensed chromosomes consist of two sister chromatids joined...
Promotes mitosis i.e. chromatin condensation through phosphorylation of condensins. The three lamins present in the nuclear lamina, lamin A, B & C, are phosphorylated...
Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that...
their publication entitled 'Real-time imaging of DNA loop extrusion by condensin' appeared in Science in 2018. "Home - Kavli Institute of Nanoscience Delft"...
decatenation of DNA entanglements, promoting sister chromatid resolution. Condensins are 5-subunit complexes that also use ATP-hydrolysis to promote chromosome...
Identification of importin α/β responsible for nuclear transport Discovery of the condensin complex essential for mitotic chromosome assembly Identification of the...
following: Clair Hoencamp et al. 3D genomics across the tree of life reveals condensin II as a determinant of architecture type. Science 372,984-989(2021).doi:10...
Condensin-2 complex subunit H2, also known as chromosome-associated protein H2 (CAP-H2) or non-SMC condensin II complex subunit H2 (NCAPH2), is a protein...
Min protein oscillations in shape-shifted bacteria 2015, discovery that condensin is a highly flexible protein structure; and first detection of DNA knots...
Condensin complex subunit 1 also known as chromosome-associated protein D2 (CAP-D2) or non-SMC condensin I complex subunit D2 (NCAPD2) or XCAP-D2 homolog...
Claire; et al. (28 May 2021). "3D genomics across the tree of life reveals condensin II as a determinant of architecture type". Science. 372 (6545): 984–989...
importin β (also known as karyopherin β) family, regulatory subunits of condensin and cohesin, separase, PIKKs (phosphatidylinositol 3-kinase-related protein...
Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the...
compact chromosome. Chromosome scaffold is made of proteins including condensin, topoisomerase IIα and kinesin family member 4 (KIF4) Chromosome scaffold...
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