Mesenchymal progenitor cell that forms a chondrocyte
This article is about the skeletal tissue. For other uses, see cartilage.
Chondroblast
Diagram of chondroblasts
Details
Identifiers
Latin
chondroblastus
TH
H2.00.03.5.00002
FMA
66783
Anatomical terms of microanatomy
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Chondroblasts, or perichondrial cells, is the name given to mesenchymal progenitor cells in situ which, from endochondral ossification, will form chondrocytes in the growing cartilage matrix. Another name for them is subchondral cortico-spongious progenitors.[1] They have euchromatic nuclei and stain by basic dyes.
These cells are extremely important in chondrogenesis due to their role in forming both the chondrocytes and cartilage matrix which will eventually form cartilage. Use of the term is technically inaccurate since mesenchymal progenitors can also technically differentiate into osteoblasts or fat. Chondroblasts are called chondrocytes when they embed themselves in the cartilage matrix, consisting of proteoglycan and collagen fibers, until they lie in the matrix lacunae. Once they embed themselves into the cartilage matrix, they grow the cartilage matrix by growing more cartilage extracellular matrix rather than by dividing further.[citation needed]
^Krüger, Jan Philipp; Hondke, Sylvia; Endres, Michaela; Pruss, Axel; Siclari, Alberto; Kaps, Christian (2012). "Human platelet-rich plasma stimulates migration and chondrogenic differentiation of human subchondral progenitor cells". Journal of Orthopaedic Research. 30 (6): 845–52. doi:10.1002/jor.22005. PMID 22058056. S2CID 25710553.
Chondroblasts, or perichondrial cells, is the name given to mesenchymal progenitor cells in situ which, from endochondral ossification, will form chondrocytes...
which consists mainly of collagen and proteoglycans. Although the word chondroblast is commonly used to describe an immature chondrocyte, the term is imprecise...
fibres. The chondrogenic layer remains undifferentiated and can form chondroblasts. Perichondrium can be found around the perimeter of elastic cartilage...
matrix of fibrocartilage is mainly made from type I collagen secreted by chondroblasts. secondary cartilaginous joints: pubic symphysis annulus fibrosis of...
Subsequently, these mesenchymal progenitor cells differentiate into chondroblasts, which actively synthesize cartilage matrix components. Thus, the initial...
a bone fracture, the progenitor cells develop into osteoblasts and chondroblasts, which are essential to the healing process. The outer fibrous layer...
the components within the extracellular matrix are produced by the chondroblasts located within the edges of the perichondrium. Elastic fibers within...
formed from condensed mesenchyme tissue, which differentiates into chondroblasts and begins secreting the molecules (aggrecan and collagen type II) that...
The periosteum is one source of precursor cells that develop into chondroblasts and osteoblasts that are essential to the healing of bone. Other sources...
A fibrocartilage callus is a temporary formation of fibroblasts and chondroblasts which forms at the area of a bone fracture as the bone attempts to heal...
Aubin JE, Liu F, Malaval L, Gupta AK (August 1995). "Osteoblast and chondroblast differentiation". Bone. 17 (2 Suppl): 77S–83S. doi:10.1016/8756-3282(95)00183-E...
Periosteum contains progenitor cells that develop into osteoblasts and chondroblasts. Pancreatic progenitor cells are among the most studied progenitors...
tissues' fibers and ground substance. Variations of fibroblasts, like chondroblasts, may also produce these substances. At small strains, elastin confers...
These cells differentiate into various cell types such as osteoblasts, chondroblasts, adipocytes, neuroectodermal cells, and hepatocytes. Bioactive mediators...
pathway-restricted SMAD protein phosphorylation hindlimb morphogenesis chondroblast differentiation cartilage development negative regulation of chondrocyte...
Research suggests that this difference is attributable to the timing of chondroblast differentiation. CYP26B1 has been shown to be over-expressed in colorectal...
progenitor cells (OPCs) and other progenitor cell populations, such as chondroblasts, myoblasts, and pericytes, as well as several different tumors including...
development reactive oxygen species metabolic process chorio-allantoic fusion chondroblast differentiation chemotaxis positive regulation of phospholipase activity...
samples. Among all myxoid tumors, EMC has the least vascular structures. Chondroblast-like lacunas may be formed, but no differentiation of hyaline cartilago...
is thought to arise from an outgrowth of immature cartilage cells (chondroblasts) from secondary ossification centers, originating from the epiphyseal...
prostate gland development limb development apoptotic cell clearance chondroblast differentiation regulation of granulocyte differentiation protein phosphorylation...
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