Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or apophyses of long bones.[1][2] It is thought to arise from an outgrowth of immature cartilage cells (chondroblasts) from secondary ossification centers, originating from the epiphyseal plate or some remnant of it.[2][3]
Chondroblastoma is very uncommon, accounting less than 1% of all bone tumors. (The chances of having this condition are roughly one in a million.)[1][3] It affects mostly children and young adults with most patients being less than 20 years of age.[1][4] Chondroblastoma shows a predilection towards the male sex, with a ratio of male to female patients of 2:1.[1][4][5] The most commonly affected site is the femur, followed by the humerus and tibia.[1][3][4][6] Less commonly affected sites include the talus and calcaneus of the foot and flat bones.[1][6]
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Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or apophyses of long bones. It is thought to arise...
(OCD). OCD involves the subchondral bone. Epiphyseal lesions include chondroblastoma and giant-cell tumor. Long bone Longitudinal section of head of left...
primitive, incompletely differentiated (or precursor) cells, e.g., chondroblastoma is composed of cells resembling the precursor of chondrocytes. Many...
as p.Gly34Arg/Val. Mutations in H3F3A and H3F3B are also found in chondroblastoma and giant cell tumor of bone. GRCh38: Ensembl release 89: ENSG00000163041...
compared to other connective tissues of the human body.[citation needed] Chondroblastomas can sometimes form, which are benign tumors that form at the sites...
hemodynamics. An aneurysmal bone cyst can arise from a pre-existing chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell tumor, or...
Médicale. 79 (24): 1126–7. PMID 5580544. Khalil, G E W (1980). "Benign chondroblastoma. A case report and review of the literature". Le Journal Médical Libanais...
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