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CgNa toxin information


CgNa is a peptide toxin isolated from the sea anemone Condylactis gigantea. It causes an increased action potential duration by slowing down the inactivation of tetrodotoxin-sensitive sodium channels.[1][2]

  1. ^ Ständker, Ludger; Béress, Lászlo; Garateix, Anoland; Christ, Torsten; Ravens, Ursula; Salceda, Emilio; Soto, Enrique; John, Harald; Forssmann, Wolf-Georg; Aneiros, Abel (August 2006). "A new toxin from the sea anemone Condylactis gigantea with effect on sodium channel inactivation". Toxicon. 48 (2): 211–220. doi:10.1016/j.toxicon.2006.05.001. PMID 16814340.
  2. ^ Salceda, Emilio; Pérez-Castells, Javier; López-Méndez, Blanca; Garateix, Anoland; Salazar, Hector; López, Omar; Aneiros, Abel; Ständker, Ludger; Béress, Lászlo; Forssmann, Wolf-Georg; Soto, Enrique; Jiménez-Barbero, Jesús; Giménez-Gallego, Guillermo (15 August 2007). "CgNa, a type I toxin from the giant Caribbean sea anemone shows structural similarities to both type I and II toxins, as well as distinctive structural and functional properties". Biochemical Journal. 406 (1): 67–76. doi:10.1042/BJ20070130. PMC 1948996. PMID 17506725.

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