Proportions of surviving mammal cells to radiation as a function of its severity (in Gy). Black lines are acute radiations, while red lines are temporally fragmented. Solid lines represent neutron radiation and dashed lines X-ray radiation.
A cell survival curve is a curve used in radiobiology. It depicts the relationship between the fraction of cells retaining their reproductive integrity and the absorbed dose of radiation. Conventionally, the surviving fraction is depicted on a logarithmic scale, and is plotted on the y-axis against dose on the x-axis.
The linear quadratic model is now most often used to describe the cell survival curve, assuming that there are two mechanisms to cell death by radiation: A single lethal event or an accumulation of harmful but non-lethal events. Cell survival fractions are exponential functions with a dose-dependent term in the exponent due to the Poisson statistics underlying the stochastic process. Whereas single lethal events lead to an exponent that is linearly related to dose, the survival fraction function for a two-stage mechanism carries an exponent proportional to the square of dose. The coefficients must be inferred from measured data, such as the Hiroshima Leukemia data. With higher orders being of lesser importance and the total survival fraction being the product of the two functions, the model is aptly called linear-quadratic.
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A cellsurvivalcurve is a curve used in radiobiology. It depicts the relationship between the fraction of cells retaining their reproductive integrity...
ionizing radiation is called a cellsurvivalcurve. For Cell-killing Particle assays, the surviving fraction of cells is used to approximate the Poisson...
a cellsurvivalcurve, the dose vs. surviving fraction have been drawn for a hypothetical group of cells with and without a rest time for the cells to...
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needed] MR is usually represented by "survivalcurves" where survival of plaque forming ability of multiply infected cells (multicomplexes) is plotted against...
after the relapse, the curve for the actual survival would look better than disease free survivalcurve. The Progression Free Survival is usually used in...
growth curve in batch culture was traditionally a part of the training of all microbiologists; the basic means requires bacterial enumeration (cell counting)...
immortalised cell line. The cells are bathed in a culture medium, which contains essential nutrients and energy sources necessary for the cells' survival. Thus...
blood cells, these genetic changes are most common alterations to molecules essential for red blood cell function (and therefore parasite survival), such...
Olanubi O, Tennakoon G, et al. (2020). "Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies". Frontiers in Immunology. 11: 1512. doi:10...
from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes...
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A1c level is only useful in individuals who have red blood cells (RBCs) with normal survivals (i.e., normal half-life). In individuals with abnormal RBCs...
As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy...
chemical characteristics of a population of cells or particles. In this process, a sample containing cells or particles is suspended in a fluid and injected...
the entire survivalcurve) EL0=∫0∞S(t)dt{\displaystyle {EL}_{0}=\int _{0}^{\infty }S(t)dt} It is important to note that both the survival function and...
are genes that promote cell growth and reproduction. Tumor suppressor genes are genes that inhibit cell division and survival. Malignant transformation...
arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells have the...
muscle. Skeletal muscle tissue consists of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other...
Keratinocytes are the major cells, constituting 95% of the epidermis, while Merkel cells, melanocytes and Langerhans cells are also present. The epidermis...
as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted...
chemotherapy administered before surgery can improve survival in patients. If no active cancer cells are present in a tissue extracted from the tumor site...
used by single cells, collectively defending against antagonists, and optimising population survival by differentiating into distinct cell types. For example...
Mauthner cell are so powerful that a single action potential gives rise to a major behavioral response: within milliseconds the fish curves its body into...
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