positive regulation of proteolysis involved in cellular protein catabolic process
positive regulation of apoptotic signaling pathway
response to organic substance
proteolysis
endoplasmic reticulum to Golgi vesicle-mediated transport
COPII vesicle coating
immune response
proteolysis involved in cellular protein catabolic process
T cell mediated cytotoxicity
apoptotic process
neutrophil degranulation
negative regulation of myelination
positive regulation of microglial cell activation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
1075
13032
Ensembl
ENSG00000109861
ENSMUSG00000030560
UniProt
P53634
P97821
RefSeq (mRNA)
NM_148170 NM_001114173 NM_001814
NM_009982 NM_001311790
RefSeq (protein)
NP_001107645 NP_001805 NP_680475
NP_001298719 NP_034112
Location (UCSC)
Chr 11: 88.27 – 88.36 Mb
Chr 7: 87.93 – 87.96 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Cathepsin C exclusion domain
re-determination of the native structure of human dipeptidyl peptidase i (cathepsin c)
Identifiers
Symbol
CathepsinC_exc
Pfam
PF08773
InterPro
IPR014882
SCOP2
1k3b / SCOPe / SUPFAM
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. In humans, it is encoded by the CTSC gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000109861 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000030560 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: CTSC cathepsin C".
^Paris A, Strukelj B, Pungercar J, Renko M, Dolenc I, Turk V (Aug 1995). "Molecular cloning and sequence analysis of human preprocathepsin C". FEBS Letters. 369 (2–3): 326–30. doi:10.1016/0014-5793(95)00777-7. PMID 7649281. S2CID 45737414.
CathepsinC (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup...
turnover. Cathepsin A (serine protease) Cathepsin B (cysteine protease) CathepsinC (cysteine protease) Cathepsin D (aspartyl protease) Cathepsin E (aspartyl...
Cathepsin B belongs to a family of lysosomal cysteine proteases known as the cysteine cathepsins and plays an important role in intracellular proteolysis...
Cathepsin D is a protein that in humans is encoded by the CTSD gene. This gene encodes a lysosomal aspartyl protease composed of a protein dimer of disulfide-linked...
Cathepsin G is a protein that in humans is encoded by the CTSG gene. It is one of the three serine proteases of the chymotrypsin family that are stored...
Cathepsin S is a protein that in humans is encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this...
Cathepsin K, abbreviated CTSK, is an enzyme that in humans is encoded by the CTSK gene. The protein encoded by this gene is a cysteine cathepsin, a lysosomal...
non-pepsin proteinase, cathepsin D-like acid proteinase, cathepsin E-like acid proteinase, cathepsin D-type proteinase) is an enzyme. Cathepsin E is a protease...
Cathepsin F is a protein that in humans is encoded by the CTSF gene. Cysteine cathepsins are a family of cysteine proteases that represent a major component...
peptidase is a type of enzyme classified under EC 3.4.14. Types include: CathepsinC, dipeptidyl peptidase-1 Dipeptidyl-peptidase II DPP3, dipeptidyl peptidase-3...
matrix. Several other cathepsins are expressed in osteoclasts including cathepsins B, C, D, E, G, and L. The function of these cysteine and aspartic proteases...
Cathepsin L2 (EC 3.4.22.43, also known as cathepsin V or cathepsin U) is a protein encoded in humans by the CTSV gene. The protein is a human cysteine...
Cathepsin L1 is a protein that in humans is encoded by the CTSL1 gene. The protein is a cysteine cathepsin, a lysosomal cysteine protease that plays a...
Cathepsin H is a protein that in humans is encoded by the CTSH gene. The protein encoded by this gene is a cysteine cathepsin, a lysosomal cysteine protease...
Cathepsin A is an enzyme that is classified both as a cathepsin and a carboxypeptidase. In humans, it is encoded by the CTSA gene. This gene encodes a...
terminal peptide sequence. This sequence can be cleaved by cathepsinC, removing 2 amino acids. Cathepsin H has also been reported to activate granzyme B. Granzyme...
DPP1 may refer to one of two enzymes: CathepsinC Diacylglycerol diphosphate phosphatase This disambiguation page lists articles associated with the same...
CTSC may refer to: CathepsinC, a protein encoded by the CTSC gene CKCS-TV, a Calgary television station branded as CTS Calgary This disambiguation page...
Cathepsin O is an enzyme encoded by the CTSO gene in humans. Cathepsin O is a cysteine cathepsin, a cysteine protease and a member of the cathepsin family...
PMID 1018879. Frohlich E, Schaumburg-Lever G, Klessen C (1993). "Immunelectron microscopic localization of cathepsin B in human exocrine glands". Journal of Cutaneous...
Chemokine receptors, Thioredoxin, Superoxide dismutase, Serine Protease, Cathepsin, Lectin. The Bathini Goud Brothers in Hyderabad, India, promote the swallowing...
Cathepsin W is a protein that in humans is encoded by the CTSW gene. The protein encoded by this gene, a member of the peptidase C1 family of cysteine...
Carboxypeptidase C (EC 3.4.16.5, carboxypeptidase Y, serine carboxypeptidase I, cathepsin A, lysosomal protective protein, deamidase, lysosomal carboxypeptidase...
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