detection of chemical stimulus involved in sensory perception of bitter taste
one-carbon metabolic process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
765
12353
Ensembl
ENSG00000131686
ENSMUSG00000028972
UniProt
P23280 Q8N4G4
P18761
RefSeq (mRNA)
NM_001215 NM_001270500 NM_001270501 NM_001270502
NM_009802
RefSeq (protein)
NP_001206 NP_001257429 NP_001257430 NP_001257431
NP_033932
Location (UCSC)
Chr 1: 8.95 – 8.98 Mb
Chr 4: 150.27 – 150.29 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Carbonic anhydrase 6 is an enzyme that in humans is encoded by the CA6 gene.[5][6] It is also called 'gustin' because of its presence in saliva, and lower-than-normal levels of salivary zinc in individuals with hypogeusia.[7][8]
^ abcGRCh38: Ensembl release 89: ENSG00000131686 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028972 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^White PS, Jensen SJ, Rajalingam V, Stairs D, Sulman EP, Maris JM, Biegel JA, Wooster R, Brodeur GM (Oct 1998). "Physical mapping of the CA6, ENO1, and SLC2A5 (GLUT5) genes and reassignment of SLC2A5 to 1p36.2". Cytogenetics and Cell Genetics. 81 (1): 60–4. doi:10.1159/000014989. PMID 9691177. S2CID 46770845.
^"Entrez Gene: CA6 carbonic anhydrase VI".
^Henkin RI, Mueller CW, Wolf RO (July 1975). "Estimation of zinc concentration of parotid saliva by flameless atomic absorption spectrophotometry in normal subjects and in patients with idiopathic hypogeusia". The Journal of Laboratory and Clinical Medicine. 86 (1): 175–80. PMID 1151138.
^Henkin RI, Lippoldt RE, Bilstad J, Edelhoch H (February 1975). "A zinc protein isolated from human parotid saliva". Proceedings of the National Academy of Sciences of the United States of America. 72 (2): 488–92. Bibcode:1975PNAS...72..488H. doi:10.1073/pnas.72.2.488. PMC 432337. PMID 1054831.
and 18 Related for: Carbonic anhydrase VI information
Carbonicanhydrase 6 is an enzyme that in humans is encoded by the CA6 gene. It is also called 'gustin' because of its presence in saliva, and lower-than-normal...
and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonicanhydrases contains a zinc ion. They are...
Carbonicanhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. Carbonicanhydrases (CAs) are a large family of zinc metalloenzymes that catalyze...
of the dissolved carbon dioxide rather than the bursting bubbles of the gas. Carbonicanhydrase 4 converts carbon dioxide to carbonic acid leading to a...
exchanger: In the lumen The H+ combines with HCO3− to form carbonic acid (H2CO3) Luminal carbonicanhydrase enzymatically converts H2CO3 into H2O and CO2 CO2 freely...
examples of zinc-containing enzymes are carbonicanhydrase and carboxypeptidase, which are vital to the processes of carbon dioxide (CO 2) regulation and digestion...
carbonicanhydrase activation has cognition-enhancing effects; but, based upon the clinical use of carbonicanhydrase inhibitors, carbonicanhydrase activation...
glaucoma. Carbonicanhydrase inhibitors, such as dorzolamide, brinzolamide, and acetazolamide, lower secretion of aqueous humor by inhibiting carbonic anhydrase...
biochemistry and nutrition. This changed in 1940 when carbonicanhydrase, an enzyme that scrubs carbon dioxide from blood, was shown to have zinc in its active...
predominantly of RuBisCO, the key enzyme in carbon fixation. By using inorganic carbon transporters and carbonicanhydrases, up to a 50-fold increase in CO2 levels...
through XO's superoxide anion byproduct, with competitive inhibition by carbonicanhydrase. Another reaction catalyzed by xanthine oxidase is the decomposition...
and Inhibitor Binding to Human CarbonicAnhydrase II: a Theoretical Study", International Workshop on CarbonicAnhydrase (Spoleto, Italy VCH Verlagsgesellschaft...
a two carbon ethyl moiety, and a terminal nitrogen, hence the name phen-ethyl-amine. The methyl group on the alpha carbon (the first carbon before the...
-A.; Bornaghi, L. F. (May 2006). "Fragment-based drug discovery of carbonicanhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene...
reduce the relative proportions of muscle-specific proteins, such as carbonicanhydrase II and myoglobin, over that predicted by the overall decrease in muscle...
Global Information
