Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound
Capsaicin
Heat
Above peak (pure capsaicin is toxic)[2]
Scoville scale
16,000,000[5] SHU
Capsaicin (8-methyl-N-vanillyl-6-nonenamide) (/kæpˈseɪsɪn/ or /kæpˈseɪəsɪn/) is an active component of chili peppers, which are plants belonging to the genus Capsicum. It is a chemical irritant and neurotoxin[6] for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related amides (capsaicinoids) are produced as secondary metabolites by chili peppers, likely as deterrents against certain mammals and fungi.[7] Pure capsaicin is a hydrophobic, colorless, highly pungent (i.e., spicy) crystalline solid.[2]
^"Capsaicin". ChemSpider, Royal Society of Chemistry, Cambridge, UK. 2018. Retrieved 9 June 2018.
^ abcd"Capsaicin". PubChem, US National Library of Medicine. 27 May 2023. Retrieved 1 June 2023.
^"Qutenza- capsaicin kit". DailyMed. 10 January 2023. Retrieved 22 February 2023.
^"Drug Approval Package: Qutenza (capsaicin) NDA #022395". U.S. Food and Drug Administration (FDA). 3 October 2013. Retrieved 22 February 2023.
^Govindarajan VS, Sathyanarayana MN (1991). "Capsicum--production, technology, chemistry, and quality. Part V. Impact on physiology, pharmacology, nutrition, and metabolism; structure, pungency, pain, and desensitization sequences". Critical Reviews in Food Science and Nutrition. 29 (6): 435–474. doi:10.1080/10408399109527536. PMID 2039598.
^Ritter S, Dinh TT (June 1990). "Capsaicin-induced neuronal degeneration in the brain and retina of preweanling rats". The Journal of Comparative Neurology. 296 (3): 447–461. doi:10.1002/cne.902960310. PMID 2358547. S2CID 5468197.
^"What Made Chili Peppers So Spicy?". Talk of the Nation. 15 August 2008.
Capsaicin (8-methyl-N-vanillyl-6-nonenamide) (/kæpˈseɪsɪn/ or /kæpˈseɪəsɪn/) is an active component of chili peppers, which are plants belonging to the...
(SHU). It is based on the concentration of capsaicinoids, among which capsaicin is the predominant component. The scale is named after its creator, American...
produce any capsaicin, although the highest concentration of capsaicin can be found in the white pith around the seeds. Most of the capsaicin in a pungent...
are widely used in many cuisines as a spice to add "heat" to dishes. Capsaicin and related compounds known as capsaicinoids are the substances that give...
mustard and curry. The primary substances responsible for pungent taste are capsaicin, piperine (in peppers) and allyl isothiocyanate (in radish, mustard and...
several cross breedings that produced an exceptionally high content of capsaicin in the locules – the plant tissue holding the seeds. The extensive curves...
potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is...
capsicum spray, OC spray, capsaicin spray, or capsicum spray is a lachrymator (tear gas) product containing the compound capsaicin as the active ingredient...
poissonii found in northern Nigeria. It is a potent functional analog of capsaicin, the active ingredient in chili peppers. Resiniferatoxin has a score of...
ingredients are highly irritant capsaicin and related capsaicinoids, that is used to deter aggressive or charging bears. Capsaicin bear spray was developed in...
naturally present in chili peppers. Although they are structurally similar to capsaicin, the substance that causes pungency in hot peppers, they largely lack...
pepper is the only member of the genus Capsicum that does not produce capsaicin, a lipophilic chemical that can cause a strong burning sensation when...
Similar to other variants the Chiltepin pepper produces and contains capsaicin which is responsible for its intense heat ranging from 100,000 to 200...
symptoms. Capsaicin, a substance found in chili peppers, may relieve joint pain from arthritis[citation needed] and other conditions. Capsaicin blocks the...
similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin but is still an ultrapotent analogue of capsaicin, with a heat intensity...
For comparison, Tabasco red pepper sauce rates at 2,500–5,000, and pure capsaicin (the chemical responsible for the pungency of pepper plants) rates at...
Dihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (Capsicum). Like capsaicin, it is an irritant. It accounts for about 22% of...
Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (Capsicum). Like capsaicin, it is an irritant. Nordihydrocapsaicin accounts...
vanilloid or capsaicin receptor 1 that reduces pain, and improves articular functions.[unreliable medical source?] It is the cis-isomer of capsaicin. Civamide...
but is commonly manufactured synthetically. It is more heat-stable than capsaicin. Nonivamide is used as a food additive to add pungency to seasonings,...
is a chemical compound that is an intermediate in the biosynthesis of capsaicin. Vanillylamine is produced from vanillin by the enzyme vanillin aminotransferase...
is the main goal of treatment. Medications applied to the skin such as capsaicin or topical anesthetics (e.g., lidocaine) are used for mild pain and can...
Homodihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (Capsicum). Like capsaicin it is an irritant. Homodihydrocapsaicin accounts...
including the characterization of the TRPV1 and TRPM8 receptors that detect capsaicin, menthol, and temperature. He is a professor at the University of California...
this is not true. Super-hots not only have more capsaicin than other peppers, but also store their capsaicin differently. In their report, Bosland et al....
the condition. Available treatments include local anesthetics, topical capsaicin, topical corticosteroids, hydroxyzine, oxcarbazepine, palmitoylethanolamide...
crushed red pepper contains fiber, capsaicin—the source of the heat in pepper chilis—and vitamins A, C, and B6. Capsaicin is believed to help kill off prostate...
2017. Capsaicin extract - The hottest sauces are made from capsaicin extract. These range from extremely hot pepper sauce blends to pure capsaicin extracts...
gas chromatography and the high-performance liquid chromatography of capsaicin and dihydrocapsaicin concentrations. Gochujang products are assigned to...
England Journal of Medicine in 1981. It occurs when the phytochemical capsaicin, which can be present in very high concentrations in certain varieties...
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