Canine cognitive dysfunction (CCD) is a disease prevalent in dogs that exhibit symptoms of dementia or Alzheimer's disease shown in humans.[1] CCD creates pathological changes in the brain that slow the mental functioning of dogs resulting in loss of memory, motor function, and learned behaviors from training early in life. In the dog's brain, the protein beta-amyloid accumulates, creating protein deposits called plaques. As the dog ages, nerve cells die, and cerebrospinal fluid fills the empty space left by the dead nerve cells.[2] Canine cognitive dysfunction takes effect in older dogs, mostly after 10 years of age. Although there is no known cause of CCD, genetic factors have been shown to contribute to the occurrence of this disease.[3]
^"Cognitive Dysfunction Syndrome in Dogs". Pets.webmd.com. Retrieved 2014-01-28.
^Andrea Menashe (2013-10-30). "Pet Talk: Canine Cognitive Dysfunction Syndrome much more manageable when caught early". OregonLive.com. Retrieved 2014-01-28.
^"Dementia (Geriatric) in Dogs". petMD. Retrieved 2014-01-28.
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