CCL3 information

CCL3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B50, 1B53, 2X69, 2X6G, 3FPU, 3H44, 3KBX, 4RA8, 4ZKB, 5D65, 5COR
Identifiers
Aliases	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3, C-C motif chemokine ligand 3
External IDs	OMIM: 182283; MGI: 98260; HomoloGene: 88430; GeneCards: CCL3; OMA:CCL3 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	36,090,169 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	83,540,181 bp
RNA expression pattern
	Top expressed in
	bone marrow; ; granulocyte; ; spleen; ; monocyte; ; bone marrow cells; ; gallbladder; ; placenta; ; testicle; ; lymph node; ; appendix;
	Top expressed in
	granulocyte; ; stroma of bone marrow; ; calvaria; ; spermatid; ; blood; ; dermis; ; secondary oocyte; ; thymus; ; islet of Langerhans; ; right kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase activity; cytokine activity; CCR5 chemokine receptor binding; chemokine activity; CCR1 chemokine receptor binding; kinase activity; phospholipase activator activity; calcium-dependent protein kinase C activity; protein binding; identical protein binding; chemoattractant activity; CCR chemokine receptor binding;
Cellular component	cytoplasm; cytosol; intracellular anatomical structure; extracellular region; extracellular space;
Biological process	G protein-coupled receptor signaling pathway; signaling; negative regulation of bone mineralization; positive regulation of protein kinase B signaling; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; response to cholesterol; positive regulation of calcium-mediated signaling; regulation of sensory perception of pain; protein kinase B signaling; monocyte chemotaxis; negative regulation of osteoclast differentiation; astrocyte cell migration; positive regulation of cell migration; positive regulation of natural killer cell chemotaxis; chemokine-mediated signaling pathway; T cell chemotaxis; cell-cell signaling; cellular response to tumor necrosis factor; eosinophil chemotaxis; cellular response to organic cyclic compound; cellular calcium ion homeostasis; negative regulation of gene expression; neutrophil chemotaxis; cell activation; MAPK cascade; chemotaxis; positive regulation of GTPase activity; positive regulation of neuron apoptotic process; positive regulation of calcium ion import; macrophage chemotaxis; positive regulation of gene expression; cytoskeleton organization; osteoblast differentiation; cellular response to interleukin-1; immune response; positive regulation of ERK1 and ERK2 cascade; regulation of cell shape; positive regulation of tumor necrosis factor production; cellular response to interferon-gamma; lymphocyte chemotaxis; inflammatory response; granulocyte chemotaxis; response to toxic substance; eosinophil degranulation; lipopolysaccharide-mediated signaling pathway; calcium ion transport; calcium-mediated signaling; exocytosis; positive regulation of calcium ion transport; positive chemotaxis; positive regulation of inflammatory response; regulation of signaling receptor activity; cytokine-mediated signaling pathway; regulation of behavior; positive regulation of microglial cell activation; positive regulation of microglial cell migration;
	Sources:Amigo / QuickGO
Orthologs
	6348
	20302
	ENSG00000278567; ENSG00000277632; ENSG00000274221
	ENSMUSG00000000982
	P10147
	P10855
	NM_002983
	NM_011337
	NP_002974
	NP_035467
	Wikidata
View/Edit Human	View/Edit Mouse

Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL3 gene.^[5]

^ ^a ^b ^c ENSG00000277632, ENSG00000274221 GRCh38: Ensembl release 89: ENSG00000278567, ENSG00000277632, ENSG00000274221 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000000982 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] ENSG00000277632, ENSG00000274221 GRCh38: Ensembl release 89: ENSG00000278567, ENSG00000277632, ENSG00000274221 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000000982 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Cite error: The named reference entrez was invoked but never defined (see the help page).

CCL3 information

and 25 Related for: CCL3 information

CCL3

Macrophage inflammatory protein

Hydrate

Chemokine

Trichloromethyl group

Reaction intermediate

Deuterated chloroform

Hexachloroethane

Terephthaloyl chloride

Acyl chloride

Interferon

Sonia Agarwal

Immunotherapy

Cytokine

Ubiquitin

Tumor necrosis factor

Transfer factor

Haematopoiesis

Hexafluoroacetone

Chromosome 17

Campylobacter jejuni

Hexachloroacetone

Interferon type I

Inflammatory cytokine

Interleukin 8