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Bromoform information


Bromoform
Skeletal formula of bromoform
Skeletal formula of bromoform
Stereo, skeletal formula of bromoform with the explicit hydrogen added
Stereo, skeletal formula of bromoform with the explicit hydrogen added
Spacefill model of bromoform

A bottle of bromoform with some in the adjacent beaker
Names
Preferred IUPAC name
Tribromomethane[1]
Other names
  • Bromoform[1]
  • Methenyl tribromide[citation needed]
  • Methyl tribromide[2]
Identifiers
CAS Number
  • 75-25-2 checkY
3D model (JSmol)
  • Interactive image
Abbreviations
  • R-20B3[citation needed]
  • UN 2515
Beilstein Reference
1731048
ChEBI
  • CHEBI:38682 checkY
ChEMBL
  • ChEMBL345248 checkY
ChemSpider
  • 13838404 checkY
DrugBank
  • DB03054 checkY
ECHA InfoCard 100.000.777 Edit this at Wikidata
EC Number
  • 200-854-6
Gmelin Reference
49500
KEGG
  • C14707 checkY
MeSH bromoform
PubChem CID
  • 5558
RTECS number
  • PB5600000
UNII
  • TUT9J99IMU checkY
UN number 2515
CompTox Dashboard (EPA)
  • DTXSID1021374 Edit this at Wikidata
InChI
  • InChI=1S/CHBr3/c2-1(3)4/h1H checkY
    Key: DIKBFYAXUHHXCS-UHFFFAOYSA-N checkY
SMILES
  • BrC(Br)Br
Properties
Chemical formula
CHBr3
Molar mass 252.731 g·mol−1
Appearance Colorless liquid
Density 2.89 g/cm3
Melting point 8.69 °C; 47.64 °F; 281.84 K
Boiling point 149.40 °C; 300.92 °F; 422.55 K
Solubility in water
3.2 g L−1 (at 30 °C)
log P 2.435
Vapor pressure 670 Pa (at 20.0 °C)
Henry's law
constant (kH)
17 μmol Pa−1 kg−1
Acidity (pKa) 13.7
Magnetic susceptibility (χ)
-82.60·10−6 cm3/mol
Refractive index (nD)
1.595
Thermochemistry
Heat capacity (C)
130.5 J K−1 mol−1
Std enthalpy of
formation fH298)
6.1–12.7 kJ mol−1
Std enthalpy of
combustion cH298)
−549.1–−542.5 kJ mol−1
Hazards
GHS labelling:
Pictograms
GHS06: Toxic GHS09: Environmental hazard
Signal word
Danger
Hazard statements
H302, H315, H319, H331, H411
Precautionary statements
P261, P273, P305+P351+P338, P311
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
3
0
0
Lethal dose or concentration (LD, LC):
LD50 (median dose)
933.0 mg kg−1 (oral, rat)
LDLo (lowest published)
1400 mg/kg (mouse, oral)
1147 mg/kg (rat, oral)[4]
LC50 (median concentration)
1151 ppm (mammal)[4]
LCLo (lowest published)
4282 ppm (rat, 4 hr)
7000 ppm (dog, 1 hr)[4]
NIOSH (US health exposure limits):
PEL (Permissible)
TWA 0.5 ppm (5 mg/m3) [skin][2]
REL (Recommended)
TWA 0.5 ppm (5 mg/m3) [skin][2]
IDLH (Immediate danger)
850 ppm[2]
Related compounds
Related alkanes
  • Dibromomethane
  • Tetrabromomethane
  • 1,1-Dibromoethane
  • 1,2-Dibromoethane
  • Tetrabromoethane
Supplementary data page
Bromoform (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

Bromoform is an organic compound with the chemical formula CHBr3. It is a colorless liquid at room temperature, with a high refractive index and a very high density. Its sweet odor is similar to that of chloroform. It is one of the four haloforms, the others being fluoroform, chloroform, and iodoform. It is a brominated organic solvent. Currently its main use is as a laboratory reagent. It is very slightly soluble in water (one part bromoform in 800 parts water) and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone and oils.

  1. ^ a b Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 661. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The retained names 'bromoform' for HCBr3, 'chloroform' for HCCl3, and 'iodoform' for HCI3 are acceptable in general nomenclature. Preferred IUPAC names are substitutive names.
  2. ^ a b c d NIOSH Pocket Guide to Chemical Hazards. "#0066". National Institute for Occupational Safety and Health (NIOSH).
  3. ^ Rumble, John (18 June 2018). CRC Handbook of Chemistry and Physics. CRC Press. pp. 3–50. ISBN 9781138561632.
  4. ^ a b c "Bromoform". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

and 29 Related for: Bromoform information

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Bromoform

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Bromoform is an organic compound with the chemical formula CHBr3. It is a colorless liquid at room temperature, with a high refractive index and a very...

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Organobromine chemistry

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using dry ice, is organohalogen compounds, of which bromoform comprises 80% by weight. Bromoform, produced by several algae, is a known toxin, though...

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Haloform reaction

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groups into carboxyl groups (R−C(=O)OH) or to produce chloroform (CHCl3), bromoform (CHBr3), or iodoform (CHI3). Note that fluoroform (CHF3) can't be prepared...

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Iodoform

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of ear hair.[citation needed] Iodoform reaction Fluoroform Chloroform Bromoform Randhawa GK, Graham R, Matharu KS, Bismuth Iodoform Paraffin Paste: History...

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Dibromochloromethane

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2017. "Public Health Statement for Bromoform and Dibromochloromethane". atsdr.cdc.gov. Retrieved 7 June 2017. "BROMOFORM AND DIBROMOCHLOROMETHANE" (PDF)...

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Trihalomethane

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chloroform in soil. Most of the haloforms — specifically, chloroform (CHCl3), bromoform (CHBr3), and iodoform (CHI3) — are easy to prepare through the haloform...

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Heavy liquid

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(Muthmanns solution), potassium tetraiodomercurate(II) (Thoulets solution), bromoform or diiodomethane which are used in mineralogy are very toxic. These toxic...

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Water chlorination

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to the chemicals and the amount ingested into the body. In high doses, bromoform mainly slows down regular brain activity, which is manifested by symptoms...

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Bromine

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this reaction. The oceans are estimated to release 1–2 million tons of bromoform and 56,000 tons of bromomethane annually. An old qualitative test for...

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Bromide

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organobromine compounds are generated by this process. Notable examples are bromoform, thousands of tons of which are produced annually in this way. The historical...

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Fluoroform

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fluoride and calcium fluoride. The exchange reaction works with iodoform and bromoform, and the exchange of the first two halogen atoms by fluorine is vigorous...

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Amyl nitrite

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solvent. For the synthesis of aryl iodides diiodomethane is used, whereas bromoform is the solvent of choice for the synthesis of aryl bromides. Amyl nitrite...

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Bromoacetone

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over-bromination, resulting in di- and tribrominated products. If a base is present, bromoform is obtained instead, by the haloform reaction. It was used in World War...

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Heavy mineral

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liquid in either a separatory funnel or centrifuge. Liquids used include bromoform, tetrabromoethane, tribromoethane, methylene iodide, and polytungstate...

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Asparagopsis taxiformis

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traditional ingredient in poke. The essential oil of limu kohu is 80% bromoform (tri-bromo-methane) by weight. It also includes many other bromine- and...

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Salt water chlorination

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trihalomethanes (THMs) of those the predominant form being bromoform. Very high levels of bromoform—up to 1.3 mg per liter, or 13 times the World Health Organization's...

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Sandmeyer reaction

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iodoarenes is diiodomethane, while for the synthesis of bromoarenes, bromoform is used. For the synthesis of chloroarenes, chloroform is the solvent...

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Halogenation

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as an oxidant. The oceans are estimated to release 1–2 million tons of bromoform and 56,000 tons of bromomethane annually.[clarification needed] The iodoform...

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Chloroform

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(inactive 26 April 2024). ISBN 978-0-85404-182-4. The retained names 'bromoform' for HCBr3, 'chloroform' for HCCl3, and 'iodoform' for HCI3 are acceptable...

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Buckminsterfullerene

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tetrahydronaphthalene 16 carbon disulfide 8 1,2,3-tribromopropane 8 xylene 5 bromoform 5 cumene 4 toluene 3 benzene 1.5 carbon tetrachloride 0.447 chloroform...

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Methylidyne radical

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and young stars, as thought earlier. Methylidyne can be prepared from bromoform. Methylene group Methylene bridge Henri A. Favre; Warren H. Powell (2014)...

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Vanadium

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iodoperoxidases. The bromoperoxidase produces an estimated 1–2 million tons of bromoform and 56,000 tons of bromomethane annually. Most naturally occurring organobromine...

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Dibromomethane

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AlCl3 CH2BrCl + HBr → CH2Br2 + HCl In the laboratory, it is prepared from bromoform using sodium arsenite and sodium hydroxide: CHBr3 + Na3AsO3 + NaOH → CH2Br2...

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John Snow

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experimented with ether, chloroform, ethyl nitrate, carbon disulfide, benzene, bromoform, ethyl bromide and dichloroethane during his lifetime. A plaque commemorates...

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Topaz

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distinguishing topaz from quartz is by placing the unset stone in a solution of bromoform or methylene iodide. Quartz will invariably float in these solutions,...

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Carbon tetrabromide

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include other brominated methanes (methyl bromide, dibromomethane and bromoform) and hydrogen bromide. This process is analogous to the chlorination of...

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List of viscosities

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CH2Cl2 0.401 Trichloromethane (chloroform) CHCl3 0.52 Tribromomethane (bromoform) CHBr3 1.89 Carbon tetrachloride CCl4 0.86 Trichloroethylene C2HCl3 0...

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Temperature dependence of viscosity

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(K) Bromine Br2 0.0445 907.6 269–302 Acetone C3H6O 0.0177 845.6 193–333 Bromoform CHBr3 0.0332 1195 278–363 Pentane C5H12 0.0191 722.2 143–313 Bromobenzene...

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Bromomethane

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displaying short descriptions of redirect targets Chloromethane Dibromomethane Bromoform Carbon tetrabromide "methyl bromide - Compound Summary". PubChem Compound...

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