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Superwarfarin information


Superwarfarins are highly potent vitamin K antagonist anticoagulants that are used as rodenticides. They are called superwarfarins because they are much more potent and long acting than warfarin.[1]

  1. ^ Feinstein, D. L; Akpa, B. S; Ayee, M. A; Boullerne, A. I; Braun, D; Brodsky, S. V; Gidalevitz, D; Hauck, Z; Kalinin, S; Kowal, K; Kuzmenko, I; Lis, K; Marangoni, N; Martynowycz, M. W; Rubinstein, I; Van Breemen, R; Ware, K; Weinberg, G (2016). "The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures". Annals of the New York Academy of Sciences. 1374 (1): 111–22. Bibcode:2016NYASA1374..111F. doi:10.1111/nyas.13085. PMC 4940222. PMID 27244102.

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Superwarfarin

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all drugs in the class. However, in the case of the second generation superwarfarins intended to kill warfarin-resistant rodents, the time of vitamin K administration...

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the second-generation anticoagulants are sometimes referred to as "superwarfarins". Vitamin K1 has been suggested, and successfully used, as antidote...

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sometimes be continued for up to nine months in cases of poisoning by "superwarfarin" rodenticides such as brodifacoum. Oral vitamin K1 is preferred over...

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