The filamentous haemagglutinin adhesin (FHA) is a large, filamentous protein that serves as a dominant attachment factor for adherence to host ciliated epithelial cells of the respiratory tract, called respiratory epithelium.[1] It is associated with biofilm formation and possesses at least four binding domains which can bind to different cell receptors on the epithelial cell surface. One notable bacterium that produces filamentous haemagglutinin adhesin is Bordetella pertussis, which uses this protein as a virulence factor.
^Locht, C; Bertin, P; Menozzi, FD; Renauld, G. (1993). "The filamentous haemagglutinin, a multifaceted adhesion produced by virulent Bordetella spp". Molecular Microbiology. 9 (4): 653–60. doi:10.1111/j.1365-2958.1993.tb01725.x. PMID 8231801.
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The filamentoushaemagglutininadhesin (FHA) is a large, filamentous protein that serves as a dominant attachment factor for adherence to host ciliated...
Department of Housing and Urban Development Filamentoushaemagglutininadhesin, a large and filamentous protein Forkhead-associated domain, a recognition...
number of the members of this family have been designated adhesins, filamentoushaemagglutinins, haem/haemopexin-binding protein, etc. Members generally...
including the pertussis toxin alone or with components such as filamentoushaemagglutinin, fimbrial antigens and pertactin. Whole-cell (wP) remains the...
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