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BerEp4 information


Comparison H&E stain (left) with BerEP4 immunohistochemistry staining (right) on a pathological section having BCC with squamous cell metaplasia. Only BCC cells are stained with BerEP4.[1]
Comparison H&E stain (left) with BerEP4 immunohistochemistry staining (right) on superficial BCC pathological sections mimicking Bowen’s Disease.[1] At bottom, columnar epithelium in normal sweat glands stain positive too.

BerEp4 (also Ber-EP4) is a histologic stain mainly used to aid in the diagnosis of basal cell carcinoma (BCC).[2] It is an antibody to EpCAM (epithelial cell adhesion molecule).[1]

  1. ^ a b c Sunjaya, Anthony Paulo; Sunjaya, Angela Felicia; Tan, Sukmawati Tansil (2017). "The Use of BEREP4 Immunohistochemistry Staining for Detection of Basal Cell Carcinoma". Journal of Skin Cancer. 2017: 1–10. doi:10.1155/2017/2692604. ISSN 2090-2905. PMC 5804366. PMID 29464122.
  2. ^ "Ber-EP4". e-immunohistochemistry.info. Retrieved 24 May 2017.

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BerEp4

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BerEp4 (also Ber-EP4) is a histologic stain mainly used to aid in the diagnosis of basal cell carcinoma (BCC). It is an antibody to EpCAM (epithelial cell...

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Epithelial cell adhesion molecule

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such conditions can therefore be assisted by immunohistochemistry using BerEp4, which is an antibody to EpCAM. A problem in EpCAM can indirectly cause...

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Carcinoembryonic antigen

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in combination with other immunohistochemistry tests, such as those for BerEp4, WT1, and calretinin. For cancers that highly express CEA, targeting CEA...

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Porocarcinoma

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(11 of 14 cases), and epithelial cell adhesion molecule as detected by BerEp4 staining (8 of 14 cases). A study on one to a few patients reported that...

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CLDN4

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effusion specimens, it has also been found to have a superior performance to BerEp4 staining. GRCh38: Ensembl release 89: ENSG00000189143 – Ensembl, May 2017...

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Mesothelioma

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(Wilms' tumour 1) MAb B72.3 Calretinin MOC-3 1 Mesothelin CD15 Cytokeratin 5 Ber-EP4 HBME-1 (human mesothelial cell 1) TTF-1 (thyroid transcription factor-1)...

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Adenomatoid tumor

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cytokeratins, WT1, D2-40, and calretinin. They are negative for MOC31, BerEP4, and vascular markers (CD31 or CD34). BAP1 expression is retained. L1 cell...

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List of histologic stains that aid in diagnosis of cutaneous conditions

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large B-cell lymphoma leg type Bcl-6 Primary cutaneous follicular lymphoma BerEp4 Desmoplastic trichoepithelioma Basal cell carcinoma Brown–Brenn Eumycotic...

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Sebaceous carcinoma

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positive with epithelial membrane antigen (EMA), cytokeratin -7 (CK-7), Ber-EP4, adipophilin, perilipin, and androgen receptor (AR). Meanwhile, SGc cells...

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CYLD cutaneous syndrome

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adhesion molecule as detected by immunohistochemical analyses using the BerEp4 antibody. The tumor tissues of trichoepithelioma-like CCS tumors may also...

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