Signs and symptoms due to benzodiazepines discontinuation in physically dependent persons
Medical condition
Benzodiazepine withdrawal syndrome
Other names
Benzo withdrawal
Diazepam is sometimes used in the treatment of benzodiazepine withdrawal.[1]
Specialty
Addiction medicine, Psychiatry
Benzodiazepines
The core structure of benzodiazepines. "R" labels denote common locations of side chains, which give different benzodiazepines their unique properties.
Pronunciation: /ˌbɛnzoʊdaɪˈæzəpiːn/
Benzodiazepine
List of benzodiazepines
Benzodiazepine overdose
Benzodiazepine dependence
Benzodiazepine misuse
Benzodiazepine withdrawal syndrome
Effects of long-term benzodiazepine use
v
t
e
Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
Typically, benzodiazepine withdrawal is characterized by sleep disturbance, irritability, increased tension and anxiety, depression, panic attacks, hand tremor, shaking, sweating, difficulty with concentration, confusion and cognitive difficulty, memory problems, dry retching and nausea, diarrhea, vomiting, loss of appetite and weight loss, burning sensations and pain in the upper spine, palpitations, headache, nightmares, tinnitus, muscular pain and stiffness, and a host of perceptual changes.[2] More serious symptoms may also occur such as depersonalization, restless legs syndrome, seizure and suicidal ideation.
Withdrawal can be managed through awareness of the withdrawal reactions, individualized taper strategies according to withdrawal severity, the addition of alternative strategies such as reassurance, and referral to benzodiazepine withdrawal support groups.[3][4]
^Cite error: The named reference pmid28328330 was invoked but never defined (see the help page).
^Petursson, H. (1994). "The benzodiazepine withdrawal syndrome". Addiction. 89 (11): 1455–9. doi:10.1111/j.1360-0443.1994.tb03743.x. PMID 7841856.
^Onyett, SR (1989). "The benzodiazepine withdrawal syndrome and its management". The Journal of the Royal College of General Practitioners. 39 (321): 160–3. PMC 1711840. PMID 2576073.
^Ashton, Heather (1991). "Protracted withdrawal syndromes from benzodiazepines". Journal of Substance Abuse Treatment. 8 (1–2): 19–28. doi:10.1016/0740-5472(91)90023-4. PMID 1675688.
and 27 Related for: Benzodiazepine withdrawal syndrome information
Benzodiazepinewithdrawalsyndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines...
Alcohol withdrawalsyndrome (AWS) is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use. Symptoms typically...
Benzodiazepine dependence (BZD dependence) defines a situation in which one has developed one or more of either tolerance, withdrawal symptoms, drug seeking...
may also occur. If stopped suddenly after long-term use, benzodiazepinewithdrawalsyndrome may occur. Older people more often develop adverse effects...
seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures. Benzodiazepines are categorized as short, intermediate...
occurrence is unclear, though the syndrome appears similar to withdrawal from other psychotropic drugs such as benzodiazepines. There is evidence that that...
and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol and other drugs. Chlordiazepoxide...
Drug withdrawal, drug withdrawalsyndrome, or substance withdrawalsyndrome, is the group of symptoms that occur upon the abrupt discontinuation or decrease...
benzodiazepine family that acts as an anxiolytic. It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawalsyndrome...
drug-seeking behavior when withdrawals occur. The severity of the benzodiazepinewithdrawalsyndrome has been described by one benzodiazepine drug misuser who stated...
order to mitigate withdrawal effects of alcohol consumption. Bromazepam is a "classical" benzodiazepine; other classical benzodiazepines include: diazepam...
of tachyphylaxis, and the possibility of development of a benzodiazepinewithdrawalsyndrome, as well as neurological complications. Bolus injections should...
known as the benzodiazepinewithdrawalsyndrome. Withdrawal from clobazam or other benzodiazepines after regular use often leads to withdrawal symptoms which...
infant syndrome and sedation in the newborn may also occur. Symptoms of floppy infant syndrome and the neonatal benzodiazepinewithdrawalsyndrome have...
the development of a severe benzodiazepinewithdrawalsyndrome in the neonate. Withdrawal symptoms from benzodiazepines in the neonate may include hypotonia...
alcohol for more than a month. A similar syndrome may occur with benzodiazepine and barbiturate withdrawal. Withdrawal from stimulants, such as cocaine and...
Peterson suffered health problems in the aftermath of severe benzodiazepinewithdrawalsyndrome. In 2021, he published his third book, Beyond Order: 12 More...
and are inactive at GABAA receptors. BenzodiazepineBenzodiazepine dependence Benzodiazepinewithdrawalsyndrome Golombok S, Lader M (August 1984). "The...
Benzodiazepine overdose (BZD OD) describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or...
cause dependence, addiction, and benzodiazepinewithdrawalsyndrome. Withdrawal from nitrazepam may lead to withdrawal symptoms which are similar to those...
lorazepam (Ativan), and alprazolam (Xanax) (see benzodiazepine dependence and benzodiazepinewithdrawalsyndrome) nonbenzodiazepine hypnotics (z-drugs) such...
drugs such as a benzodiazepinewithdrawalsyndrome from discontinuing benzodiazepine tranquilizers or sleeping pills alcohol withdrawal can also cause...
neuropsychiatric behavioral syndrome that is characterized by abnormal movements, immobility, abnormal behaviors, and withdrawal. The onset of catatonia can...
benzodiazepines can lead to tolerance, physical dependence, benzodiazepinewithdrawalsyndrome upon discontinuation, and long-term worsening of sleep, especially...
Global Information
