Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Azelaic acid (AzA) is an organic compound with the formula HOOC(CH2)7COOH.[3] This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley. It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of a number of hair and skin conditioners.[4] AzA inhibits tyrosinase.[5]
^ abSigma-Aldrich catalog Archived April 9, 2008, at the Wayback Machine
^ abBretti, C.; Crea, F.; Foti, C.; Sammartano, S. (2006). "Solubility and Activity Coefficients of Acidic and Basic Nonelectrolytes in Aqueous Salt Solutions. 2. Solubility and Activity Coefficients of Suberic, Azelaic, and Sebacic Acids in NaCl(aq), (CH3)4NCl(aq), and (C2H5)4NI(aq) at Different Ionic Strengths and at t = 25 °C". J. Chem. Eng. Data. 51 (5): 1660–1667. doi:10.1021/je060132t.
^Del Rosso, James Q. (2006-02-01). "The use of topical azelaic acid for common skin disorders other than inflammatory rosacea". Cutis. 77 (2 Suppl): 22–24. ISSN 0011-4162. PMID 16566285.
^Cite error: The named reference Boy was invoked but never defined (see the help page).
^Cite error: The named reference TyrosinaseInhibitor was invoked but never defined (see the help page).
Azelaicacid (AzA) is an organic compound with the formula HOOC(CH2)7COOH. This saturated dicarboxylic acid exists as a white powder. It is found in wheat...
Treatments applied directly to the affected skin, such as azelaicacid, benzoyl peroxide, and salicylic acid, are commonly used. Antibiotics and retinoids are...
old. Azelaicacid was prepared by oxidation of oleic acid with potassium permanganate, but now by oxidative cleavage of oleic acid with chromic acid or...
carboxylic acid group yields oleyl alcohol. Ozonolysis of oleic acid is an important route to azelaicacid. The coproduct is nonanoic acid: H17C8CH=CHC7H14CO2H...
hydroquinone, however it is less effective at lightening and also carcinogenic. Azelaicacid is another option. Mercury was commonly used as a skin lightening agent...
candles. Sebacic acid is a derivative of castor oil. In the industrial setting, sebacic acid and its homologues such as azelaicacid can be used as a...
viable antibiotic against MuH strains. Other antibiotic agents, such as azelaicacid, nitrofurazone, silver sulfadiazine, and ramoplanin have been shown to...
such as hydroquinone, azelaicacid, and kojic acid. Some are available without prescription, such as niacinamide, l-ascorbic acid,[citation needed] retinoids...
is practiced in the production of azelaicacid ((CH2)7(CO2H)2) from oleic acid. Short- and medium-chain fatty acids are absorbed directly into the blood...
available or under research, including azelaicacid, kojic acid, retinoids, cysteamine, topical steroids, glycolic acid, and other substances. One of these...
Some research suggests that the common acne medications retinoids and azelaicacid are beneficial and do not cause increased pigmentation of the skin. If...
due to risk of harm to the fetus. Azelaicacid (20%) is thought to decrease the activity of melanocytes. Tranexamic acid by mouth has shown to provide rapid...
unsaturated fatty acids to value-added derivatives. Ozonolysis of oleic acid is an important route to azelaicacid. The coproduct is nonanoic acid: CH3(CH2)7CH=CH(CH2)7CO2H}...
benzoyl peroxide, antibiotics and azelaicacid]" [Acne therapy with topical benzoyl peroxide, antibiotics and azelaicacid]. Journal der Deutschen Dermatologischen...
agents, such as hydroquinone, tretinoin, topical cysteamine, azelaicacid, or alpha hydroxy acids. Differently from the melanotic nevi and the verrucous nevi...
Medications with good evidence include topical metronidazole, ivermectin and azelaicacid. Good evidence medications taken by mouth include brimonidine, and doxycycline...
furfur, lightening of the skin occurs due to the fungus's production of azelaicacid, which has a slight bleaching effect. Tinea versicolor may be diagnosed...
may include topical agents like hydroquinone, retinoids, ascorbic acid, and azelaicacid, as well as chemical peels or laser therapy to promote skin renewal...
contains esters of the acid. Together with azelaicacid, it is produced industrially by ozonolysis of oleic acid. CH 3 ( CH 2 ) 7 CH = CH ( CH 2 ) 7 CO 2...
produce pelargonic acid, and azelaicacid. In another application it was possible to recover oleic acid, linoleic acid and linolenic acid and fermented, using...
depigmentation agents. Some common depigmentation agents such as azelaicacid and kojic acid seem to be inefficient in this case, however other agents might...
chemical peeling are salicylic acid, glycolic acid, azelaicacid, 30% salicylic acid in ethanol, and trichloroacetic acid (TCA). Prior to chemexfoliation...
approved by the FDA include alpha hydroxy acids (naturally available in small amounts in citrus fruits), Azelaicacid, and zinc. It is not thought that they...
Maybury C (October 2023). "A systematic review to evaluate the efficacy of azelaicacid in the management of acne, rosacea, melasma and skin aging". J Cosmet...
Frank (1 May 2020). "Topical azelaicacid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne". The Cochrane Database...
inhibitors are the following: Azelaicacid 4-Butylresorcinol Hydroquinone L-ascorbic acid - Vitamin C Tranexamic acid While albinism is common, there...
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