Proposed mechanism for anti-sRNA relief of sRNA mediated translation inhibition.[1]Antisense small RNA identification using RNA Array
Anti GcvB sRNA
Predicted secondary structure and sequence conservation Anti GcvB sRNA
Identifiers
Rfam
RF02702
Other data
Domain(s)
Bacteria
GO
GO:0045975
SO
SO:0000370
PDB structures
PDBe
Anti stx2 sRNA
Predicted secondary structure and sequence conservation Anti stx2 sRNA
Identifiers
Rfam
RF02703
Other data
Domain(s)
Bacteria
GO
GO:0045975
SO
SO:0000370
PDB structures
PDBe
Antisense small RNAs (abbreviated anti small RNA or anti-sRNA) are short RNA sequences (about 50-500 nucleotides long) that are complementary to other small RNA (sRNA) in the cell.[2]
sRNAs can repress translation via complementary base-pairing with their target mRNA sequence.[3] Anti-sRNAs function by complementary pairing with sRNAs before the mRNA can be bound, thus freeing the mRNA and relieving translation inhibition.[4] Anti-sRNAs lead to higher expression of mRNAs by inhibiting the action of sRNAs.[1]Sponge RNA is another term used to describe anti-sRNAs.[5]
^Bhatt S, Egan M, Jenkins V, Muche S, El-Fenej J (2016). "Escherichia coli". Frontiers in Cellular and Infection Microbiology. 6: 105. doi:10.3389/fcimb.2016.00105. PMC 5030294. PMID 27709103.
^Grosshans H, Filipowicz W (January 2008). "Molecular biology: the expanding world of small RNAs". Nature. 451 (7177): 414–6. Bibcode:2008Natur.451..414G. doi:10.1038/451414a. PMID 18216846. S2CID 205035466.
^Papenfort, Kai; Vanderpool, Carin K. (May 2015). "Target activation by regulatory RNAs in bacteria". FEMS Microbiology Reviews. 39 (3): 362–378. doi:10.1093/femsre/fuv016. ISSN 0168-6445. PMC 4542691. PMID 25934124.
^Iosub, Ira Alexandra; van Nues, Robert Willem; McKellar, Stuart William; Nieken, Karen Jule; Marchioretto, Marta; Sy, Brandon; Tree, Jai Justin; Viero, Gabriella; Granneman, Sander (2020-05-01). Wade, Joseph T; Manley, James L; Luisi, Ben F (eds.). "Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation". eLife. 9: e54655. doi:10.7554/eLife.54655. ISSN 2050-084X. PMC 7213987. PMID 32356726. S2CID 218475140.
Antisense smallRNAs (abbreviated antismallRNA or anti-sRNA) are short RNA sequences (about 50-500 nucleotides long) that are complementary to other small RNA...
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Ribosomal RNA is transcribed from ribosomal DNA (rDNA) and then bound to ribosomal proteins to form small and large ribosome subunits. rRNA is the physical...
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ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
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Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded RNA that...
conserved stem-loops involved in the interaction with several target mRNAs (PhoR, MotE, anti-σE1, GntR, FgA, TrpC). In Sinorhizobium meliloti RcsR1 less conserved...
Small nucleolar RNA TBR2 is a non-coding RNA (ncRNA) molecule identified in Trypanosoma brucei which functions in the modification of other small nuclear...
the small nucleolar RNA ACA40 belongs to the H/ACA family of snoRNAs and guides the pseudouridylation of 28S rRNA subunit at position U4565. snoRNA ACA40...
for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA Non-coding RNA Gribaldo S, Brochier-Armanet...
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The RNA world is a hypothetical stage in the evolutionary history of life on Earth, in which self-replicating RNA molecules proliferated before the evolution...
molecular biology, Small nucleolar RNA ACA49 is a snoRNA, originally cloned in 2004 from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody...
In molecular biology, Small nucleolar RNA SNORA48 is a pseudouridylation guide H/ACA box snoRNA. This snoRNA was cloned in 2004 from a HeLa cell extract...
(pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins...
Small nucleolar RNA TBR17 is a non-coding RNA (ncRNA) molecule identified in Trypanosoma brucei which functions in the modification of other small nuclear...
Small nucleolar RNA TBR7 is a non-coding RNA (ncRNA) molecule identified in Trypanosoma brucei which functions in the modification of other small nuclear...
refers to the structure of nucleic acids such as DNA and RNA. Chemically speaking, DNA and RNA are very similar. Nucleic acid structure is often divided...
to the ribosome by transfer RNA (tRNA) molecules, which enter the ribosome and bind to the messenger RNA chain via an anti-codon stem loop. For each coding...
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