Zinc finger protein ZFPM1 information

ZFPM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XU7
Identifiers
Aliases	ZFPM1, FOG, FOG1, ZC2HC11A, ZNF408, ZNF89A, zinc finger protein, FOG family member 1
External IDs	OMIM: 601950; MGI: 1095400; HomoloGene: 7606; GeneCards: ZFPM1; OMA:ZFPM1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	88,537,031 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	123,063,990 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; mucosa of ileum; ; nasal epithelium; ; pylorus; ; cardia; ; parotid gland; ; ventral tegmental area; ; subthalamic nucleus; ; external globus pallidus; ; vena cava;
	Top expressed in
	tibiofemoral joint; ; fetal liver hematopoietic progenitor cell; ; left lobe of liver; ; epithelium of stomach; ; pyloric antrum; ; internal carotid artery; ; external carotid artery; ; spleen; ; duodenum; ; human fetus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription factor binding; metal ion binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; nucleic acid binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; transcription regulator complex; transcription repressor complex; nucleoplasm; nucleus;
Biological process	megakaryocyte development; megakaryocyte differentiation; negative regulation of mast cell differentiation; negative regulation of fat cell differentiation; regulation of transcription, DNA-templated; homeostasis of number of cells; ventricular septum morphogenesis; outflow tract morphogenesis; platelet formation; blood coagulation; cardiac muscle tissue morphogenesis; negative regulation of transcription by RNA polymerase II; negative regulation of protein binding; transcription, DNA-templated; regulation of chemokine production; atrial septum morphogenesis; heart development; atrioventricular valve morphogenesis; granulocyte differentiation; embryonic hemopoiesis; regulation of definitive erythrocyte differentiation; T-helper cell lineage commitment; primitive erythrocyte differentiation; mitral valve formation; tricuspid valve formation; definitive erythrocyte differentiation; positive regulation of transcription by RNA polymerase II; erythrocyte differentiation; regulation of megakaryocyte differentiation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	161882
	22761
	ENSG00000179588
	ENSMUSG00000049577
	Q8IX07
	O35615
	NM_153813
	NM_009569
	NP_722520
	NP_033595
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein ZFPM1 also known as friend of GATA protein 1 (FOG-1) is a protein that in humans is encoded by the ZFPM1 gene.^[5] It is a cofactor of the GATA1 transcription factor.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000179588 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000049577 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ZFPM1 zinc finger protein, multitype 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000179588 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000049577 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ZFPM1 zinc finger protein, multitype 1".

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