WNK3 information

WNK3
Identifiers
Aliases	WNK3, PRKWNK lysine deficient protein kinase 3
External IDs	OMIM: 300358; MGI: 2652875; HomoloGene: 32493; GeneCards: WNK3; OMA:WNK3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	54,358,642 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	150,103,148 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; caput epididymis; ; secondary oocyte; ; seminal vesicula; ; internal globus pallidus; ; retinal pigment epithelium; ; ganglionic eminence; ; postcentral gyrus; ; endothelial cell; ; superior vestibular nucleus;
	Top expressed in
	hand; ; lateral hypothalamus; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; dorsomedial hypothalamic nucleus; ; mammillary body; ; medial vestibular nucleus; ; ventral tegmental area; ; inferior colliculus; ; arcuate nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; kinase activity; protein serine/threonine kinase activity; protein binding; chloride channel inhibitor activity; ATP binding; potassium channel inhibitor activity;
Cellular component	cytoplasm; bicellular tight junction; adherens junction; cytosol;
Biological process	phosphorylation; negative regulation of apoptotic process; protein phosphorylation; positive regulation of ion transmembrane transporter activity; positive regulation of peptidyl-threonine phosphorylation; positive regulation of sodium ion transport; protein autophosphorylation; positive regulation of sodium ion transmembrane transporter activity; negative regulation of pancreatic juice secretion; positive regulation of calcium ion transport; intracellular signal transduction; regulation of calcium ion import; protein localization to plasma membrane; positive regulation of protein localization to plasma membrane; ion homeostasis; negative regulation of sodium ion transport; positive regulation of potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	65267
	279561
	ENSG00000196632
	ENSMUSG00000041245
	Q9BYP7
	Q80XP9
	NM_001002838; NM_020922; NM_001395166
	NM_001271678; NM_001271679
	NP_001002838; NP_065973
	NP_001258607; NP_001258608
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a protein that in humans is encoded by the WNK3 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196632 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041245 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: WNK lysine deficient protein kinase 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196632 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041245 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: WNK lysine deficient protein kinase 3".

WNK3 information

and 8 Related for: WNK3 information

WNK3

Distal convoluted tubule

LINGO1

WNK

Protein kinase domain

WNK1

PHF8

Chloride potassium symporter 5