Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits, berries and vegetables. It is also a generic prescription medication and in some countries is sold as a non-prescription dietary supplement. As a therapy, it is used to prevent and treat scurvy, a disease caused by vitamin C deficiency.
Vitamin C is an essential nutrient involved in the repair of tissue, the formation of collagen, and the enzymatic production of certain neurotransmitters. It is required for the functioning of several enzymes and is important for immune system function.[6] It also functions as an antioxidant. Vitamin C may be taken by mouth or by intramuscular, subcutaneous or intravenous injection. Various health claims exist on the basis that moderate vitamin C deficiency increases disease risk, such as for the common cold, cancer or COVID-19. There are also claims of benefits from vitamin C supplementation in excess of the recommended dietary intake for people who are not considered vitamin C deficient. Vitamin C is generally well-tolerated. Large doses may cause gastrointestinal discomfort, headache, trouble sleeping, and flushing of the skin. The United States Institute of Medicine recommends against consuming large amounts.[7]: 155–165
Most animals are able to synthesize their own vitamin C. However, apes (including humans) and monkeys (but not all primates), most bats, most fish, some rodents, and certain other animals must acquire it from dietary sources because a gene for a synthesis enzyme has mutations that render it dysfunctional.
Vitamin C was discovered in 1912, isolated in 1928, and in 1933, was the first vitamin to be chemically produced. Partly for its discovery, Albert Szent-Györgyi was awarded the 1937 Nobel Prize in Physiology or Medicine.
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^"Ascorbic acid 100mg tablets". (emc). October 29, 2018. Archived from the original on September 21, 2020. Retrieved October 12, 2020.
^"Ascor- ascorbic acid injection". DailyMed. October 2, 2020. Archived from the original on October 29, 2020. Retrieved October 12, 2020.
^Cite error: The named reference NIH2021 was invoked but never defined (see the help page).
^"Vitamin C". Chem Spider. Royal Society of Chemistry. Archived from the original on July 24, 2020. Retrieved July 25, 2020.
^"Vitamin C". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR. July 1, 2018. Archived from the original on July 12, 2019. Retrieved June 19, 2019.
^Institute of Medicine (US) Panel on Dietary Antioxidants Related Compounds (2000). "Vitamin C". Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: The National Academies Press. pp. 95–185. doi:10.17226/9810. ISBN 978-0-309-06935-9. PMID 25077263. Archived from the original on September 2, 2017. Retrieved September 1, 2017.
VitaminC (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits, berries and vegetables. It is also a...
folates) Vitamin B12 (cobalamins) VitaminC (ascorbic acid and ascorbates) Vitamin D (calciferols) Vitamin E (tocopherols and tocotrienols) Vitamin K (phylloquinones...
VitaminC megadosage is a term describing the consumption or injection of vitaminC (ascorbic acid) in doses well beyond the current United States Recommended...
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Vitamin deficiency is the condition of a long-term lack of a vitamin. When caused by not enough vitamin intake it is classified as a primary deficiency...
plants began producing non-marine antioxidants such as ascorbic acid (vitaminC), polyphenols, and tocopherols. The evolution of angiosperm plants between...
Vitamin A is a fat-soluble vitamin and an essential nutrient for animals. The term "vitamin A" encompasses a group of chemically related organic compounds...
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Taking vitaminC with aspirin has been investigated as a method of protecting the stomach lining. In trials vitaminC-releasing aspirin (ASA-VitC) or a...
Scurvy is a disease resulting from a lack of vitaminC (ascorbic acid). Early symptoms of deficiency include weakness, fatigue, and sore arms and legs...
types of organisms have different essential nutrients. Ascorbic acid (vitaminC) is essential to humans and some animal species, but most other animals...
ascorbic acid (commonly known as VitaminC). None of his ideas concerning the medical usefulness of large doses of vitamins have gained much acceptance in...
of said vitamin and prevents the symptoms of deficiency of said vitamin. Early research identified vitamins by their ability to cure vitamin-specific...
a risk of adverse health effects. Many multivitamin formulas contain vitaminC, B1, B2, B3, B5, B6, B7, B9, B12, A, E, D2 (or D3), K, potassium, iodine...
Antioxidant vitamins as dietary supplements had been proposed as having benefits if consumed during pregnancy. For the combination of vitamin E with vitaminC supplemented...
stress is observed in septic shock, with circulating levels of copper and vitaminC being decreased. Diastolic blood pressure falls during the early stages...
compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). The major natural source of vitamin D is synthesis of cholecalciferol...
(table). It is particularly rich in vitaminC (112% DV) and vitamin K (38% DV), has a moderate content of vitamin E (10% DV), with no other micronutrients...
either raw or cooked. Broccoli is a particularly rich source of vitaminC and vitamin K. Contents of its characteristic sulfur-containing glucosinolate...
calories, and is a rich source of vitaminC – containing 158% of the Daily Value (DV) – vitamin A (20%), and vitamin B6 (23% DV), with moderate contents...
VitaminC supplementation does not affect the incidence of the common cold, but may reduce its duration. There is no conclusive evidence that vitamin...
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