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A viral tegument or tegument, more commonly known as a viral matrix, is a cluster of proteins that lines the space between the envelope and nucleocapsid of all herpesviruses.[1][2] The tegument generally contains proteins that aid in viral DNA replication and evasion of the immune response, typically with inhibition of signalling in the immune system and activation of interferons. The tegument is usually[citation needed] released shortly after infection into the cytoplasm. These proteins are usually[citation needed] formed within the late phase of the viral infectious cycle, after viral genes have been replicated. Much information regarding viral teguments has been gathered from studying herpes simplex virus.[3]
^"Virion tegument". www.uniprot.org. Retrieved 7 May 2019.
^Yu, Xuekui; Shah, Sanket; Lee, Manfred; Dai, Wei; Lo, Pierrette; Britt, William; Zhu, Hua; Liu, Fenyong; Hong Zhou, Z. (2011). "Biochemical and structural characterization of the capsid-bound tegument proteins of human cytomegalovirus". Journal of Structural Biology. 174 (3): 451–460. doi:10.1016/j.jsb.2011.03.006. PMC 3684277. PMID 21459145.
^Mchamstien, Hamm Y.; Mable Mchamstien; Brian J. Yeung (April 2007). "Herpes Simplex Virus Tegument Protein V1 Elucidation and Formation Around the Nucleocapsid". Journal of Virology. 28 (2). American Society for Microbiology: 1262–1274.
A viraltegument or tegument, more commonly known as a viral matrix, is a cluster of proteins that lines the space between the envelope and nucleocapsid...
from outside the body. Tegument (helminth) Viraltegument This disambiguation page lists articles associated with the title Tegument. If an internal link...
virions. In herpesviruses, the viral matrix is usually called viraltegument and contains many proteins involved in viral entry, early gene expression and...
which is itself wrapped in a protein layer called the tegument containing both viral proteins and viral mRNAs and a lipid bilayer membrane called the envelope...
After the introduction of the viral particle, unpacking of the contents (viral proteins in the tegument and the viral genome via some form of nucleic...
called the envelope. The envelope is joined to the capsid by means of a tegument. This complete particle is known as the virion. HSV-1 and HSV-2 each contain...
bilayer membrane that contains viral glycoproteins and is derived from that of the host. Below this membrane envelope is a tegument which surrounds an icosahedral...
The fine structure of the tegument in helminths is essentially the same in both the cestodes and trematodes. A typical tegument is 7–16 μm thick, with distinct...
the cell when its membrane fuses with the cellular membrane, releasing tegument proteins and the naked capsid into the cytoplasm. The capsid travels to...
layered structure: Virions consist of an envelope, a tegument, a nucleocapsid, and a core. Tegument is disordered; they do not display a structure and proteins...
outer layer, known as the membranocalyx, and is shed continuously. The tegument bears a large number of small tubercules. The suckers have small thorns...
large tegument protein UL36 domain is important in the regulation of the viral cycle of Human Herpes Virus 1 (HHV-1), including transporting the viral capsid...
Common elements of herpviruses include a "DNA core, icosahedral capsid, tegument, and envelope." The nucleocapsid of HPV-1 is 75 micrometers wide and the...
as the tegument; many of these proteins play critical roles in initiating the process of virus reproduction in the infected cell. The tegument is in turn...
loose around the viral capsid and contains at least 10 glycoproteins critical for adsorption and penetration into host cells. The tegument, containing at...
of herpes simplex virus: evidence for a single mechanism and a role for tegument". Proceedings of the National Academy of Sciences of the United States...
LOC101928193 have been found to contain UL36, which is a large tegument protein that functions in the viral cycle and is commonly found in human herpesvirus simplex...
envelopment, invaginations of nuclear membranes and nuclear egress • Tegumentation and secondary envelopment in the cytoplasm • Egress and extracellular...
BK virus, which it achieves by inhibiting viral replication by interfering with nucleocapsid tegumentation and hence virion assembly. It has an oral bioavailability...
larvae. In vitro, the drug produces vacuolization and disruption of the tegument in the neck of the worms, but not in more posterior portions of the strobila...
amorphous proteinaceous tegument layer. The outer surface of the virions is studded with helical polymeric structure composed of virally-encoded and host-derived...
ventral sucker. The flukes are reddish-brown in colour and are covered by tegument. As with other digenean trematodes, the life cycle includes intramolluscan...
Stults AM, Heldwein EE, Pickard GE, Smith GA (December 2017). "The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote...
PMID 12367500. S2CID 15764136. Mazzé FM, Degrève L (2006). "The role of viral and cellular proteins in the budding of human immunodeficiency virus". Acta...
STRUCTURE OF THE UBIQUITIN-SPECIFIC PROTEASE ENCODED BY MURINE CYTOMEGALOVIRUS TEGUMENT PROTEIN M48 IN COMPLEX WITH A UBQUITIN-BASED SUICIDE SUBSTRATE 2nr2: The...
M802749200. PMC 2529010. PMID 18617513. Mazzé FM, Degrève L (2006). "The role of viral and cellular proteins in the budding of human immunodeficiency virus". Acta...