VAMP1 information

VAMP1
Identifiers
Aliases	VAMP1, SPAX1, SYB1, VAMP-1, vesicle associated membrane protein 1, CMS25
External IDs	OMIM: 185880; MGI: 1313276; HomoloGene: 40678; GeneCards: VAMP1; OMA:VAMP1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	6,470,677 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	125,222,927 bp
RNA expression pattern
	Top expressed in
	pons; ; Brodmann area 23; ; primary visual cortex; ; superior vestibular nucleus; ; lateral nuclear group of thalamus; ; spinal ganglia; ; endothelial cell; ; middle temporal gyrus; ; dorsal motor nucleus of vagus nerve; ; inferior olivary nucleus;
	Top expressed in
	pontine nuclei; ; deep cerebellar nuclei; ; medulla oblongata; ; medial vestibular nucleus; ; anterior horn of spinal cord; ; dorsal tegmental nucleus; ; facial motor nucleus; ; inferior colliculus; ; lateral geniculate nucleus; ; superior colliculus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	SNAP receptor activity; protein binding; syntaxin binding;
Cellular component	synaptic vesicle membrane; synapse; integral component of membrane; mitochondrion; tertiary granule membrane; azurophil granule membrane; cell junction; integral component of plasma membrane; neuron projection; membrane; cell surface; specific granule membrane; mitochondrial outer membrane; cytoplasmic vesicle membrane; cytoplasmic vesicle; cytosol; SNARE complex; integral component of synaptic vesicle membrane; neuromuscular junction; presynapse; glutamatergic synapse;
Biological process	SNARE complex assembly; vesicle fusion; vesicle-mediated transport; exocytosis; synaptic vesicle priming; regulation of synaptic vesicle fusion to presynaptic active zone membrane;
	Sources:Amigo / QuickGO
Orthologs
	6843
	22317
	ENSG00000139190
	ENSMUSG00000030337
	P23763
	Q62442
	NM_001297438; NM_014231; NM_016830; NM_199245
	NM_001080557; NM_009496
	NP_001284367; NP_055046; NP_058439; NP_954740
	NP_001074026; NP_033522
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicle-associated membrane protein 1 (VAMP1) is a protein that in humans is encoded by the VAMP1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000139190 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030337 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Archer BT, Ozçelik T, Jahn R, Francke U, Südhof TC (October 1990). "Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2". The Journal of Biological Chemistry. 265 (28): 17267–73. doi:10.1016/S0021-9258(17)44898-8. PMID 1976629.
^ "Entrez Gene: VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000139190 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030337 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1976629-5] Archer BT, Ozçelik T, Jahn R, Francke U, Südhof TC (October 1990). "Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2". The Journal of Biological Chemistry. 265 (28): 17267–73. doi:10.1016/S0021-9258(17)44898-8. PMID 1976629.

[entrez-6] "Entrez Gene: VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)".

VAMP1 information

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VAMP1

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Synaptobrevin

TMEM101

Rosie Hardman

VAPB