UQCRH information

UQCRH
Identifiers
Aliases	UQCRH, QCR6, UQCR8, ubiquinol-cytochrome c reductase hinge protein
External IDs	OMIM: 613844; MGI: 3641869; HomoloGene: 103848; GeneCards: UQCRH; OMA:UQCRH - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	46,316,776 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; left ventricle; ; superior frontal gyrus; ; dorsolateral prefrontal cortex; ; prefrontal cortex; ; cerebellar hemisphere; ; Brodmann area 9; ; hypothalamus; ; rectum; ; nucleus accumbens;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; ubiquinol-cytochrome-c reductase activity;
Cellular component	mitochondrial inner membrane; respirasome; membrane; mitochondrion; mitochondrial respirasome; mitochondrial respiratory chain complex III;
Biological process	aerobic respiration; oxidative phosphorylation; proton transmembrane transport; mitochondrial electron transport, ubiquinol to cytochrome c;
	Sources:Amigo / QuickGO
Orthologs
	7388
	100042918
	ENSG00000173660
	ENSMUSG00000037438
	P07919
	n/a
	NM_006004; NM_001297565; NM_001297566
	n/a
	NP_001284494; NP_001284495; NP_005995
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome b-c1 complex subunit 6, mitochondrial is a protein that in humans is encoded by the UQCRH gene.^[4]^[5]

Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex; E.C. 1.10.2.2), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b) and ten nuclear genes: UQCRC1, UQCRC2, Cytochrome c1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and "Rieske-associated protein".

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173660 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ohta S, Goto K, Arai H, Kagawa Y (Jan 1988). "An extremely acidic amino-terminal presequence of the precursor for the human mitochondrial hinge protein". FEBS Lett. 226 (1): 171–5. doi:10.1016/0014-5793(87)80573-2. PMID 2826252.
^ "Entrez Gene: UQCRH ubiquinol-cytochrome c reductase hinge protein". Archived from the original on 2024-04-28. Retrieved 2017-09-17.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000173660 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2826252-4] Ohta S, Goto K, Arai H, Kagawa Y (Jan 1988). "An extremely acidic amino-terminal presequence of the precursor for the human mitochondrial hinge protein". FEBS Lett. 226 (1): 171–5. doi:10.1016/0014-5793(87)80573-2. PMID 2826252.

[entrez-5] "Entrez Gene: UQCRH ubiquinol-cytochrome c reductase hinge protein". Archived from the original on 2024-04-28. Retrieved 2017-09-17.

UQCRH information

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